The download/pathways/ directory contains metabolic pathway information. The pathways were created at CGD using the Pathway Tools software, which is developed and maintained by the Bioinformatics Research Group at SRI International (see http://bioinformatics.ai.sri.com/ptools/). The pathway predictions are being manually reviewed and curated at CGD, as described in more detail on our Pathways Help page (http://www.candidagenome.org/help/BiochemPathwaysHelp.shtml). The genes from C. albicans SC5314 were used as input by the prediction software, but the manually curated pathway descriptions consider the pathway within the broader context of metabolism within Candida species in general. --------------------------- pathwaysAndGenes.tab This tab-delimited file contains a list of the metabolic pathways in CGD, with lists of the genes that encode the enzymes within each pathway. Columns: 1. UNIQUE-ID; the unique identifier (also called the "frame name") of the pathway 2. NAME; the common name of the pathway 3. GENE-NAMES; colon-delimited list of CGD standard names of the genes that encode the enzymes within the pathway 4. GENE-IDS; colon-delimited list of the systematic names (orf19 names) of the genes that encode the enzymes within the pathway This file is updated weekly. --------------------------- calbibase.ocelot.gz This file contains the CGD metabolic pathway information in the format that is read by the Pathway Tools software from SRI. Information about copying pathway databases in this format is available at: http://bioinformatics.ai.sri.com/ptools/copy-patho-db.html The file is gzip compressed. There are several freely available software options for decompressing gzipped files using Windows. The software and other useful information is available on these web sites: - WinZip (http://www.winzip.com/) - Stuffit (http://www.stuffit.com/) - Gzip (http://www.gzip.org/ and the gzip user's manual: http://www.math.utah.edu/docs/info/gzip_toc.html --------------------------- URL: www.candidagenome.org Contact: http://www.candidagenome.org/cgi-bin/suggestion Funding: NIDCR at US NIH, grant number 1-R01-DE015873-01