UniqueID (Johnson lab) orf6 # orf19# Name (Candida Annotation Working Group) Annotation (Candida Annotation Working Group) Gene class(es) rfg1/WT #1 rfg1/WT #2 rfg1/WT #3 rfg1/WT #4 nrg1/WT #1 nrg1/WT #2 nrg1/WT #3 nrg1/WT #4 nrg1/WT #5 nrg1/WT #6 tup1/WT #1 tup1/WT #2 tup1/WT #3 tup1/WT #4 tup1/WT #5 tup1/WT #6 37 Ser 1h/Zero #1 37 Ser 1h/Zero #2 37 Ser 2h/Zero #1 37 Ser 2h/Zero #2 37 Ser 3h/Zero #1 37 Ser 3h/Zero #2 37 Ser 5h/Zero #1 37 Ser 5h/Zero #2 37 1h/Zero #1 37 1h/Zero #2 37 2h/Zero #1 37 2h/Zero #2 37 3h/Zero #1 37 3h/Zero #2 37 5h/Zero #1 37 5h/Zero #2 30 Ser 1h/Zero #1 30 Ser 1h/Zero #2 30 Ser 2h/Zero #1 30 Ser 2h/Zero #2 30 Ser 3h/Zero #1 30 Ser 3h/Zero #2 30 Ser 5h/Zero #1 30 Ser 5h/Zero #2 30 1h/Zero #1 30 1h/Zero #2 30 2h/Zero #1 30 2h/Zero #2 30 3h/Zero #1 30 3h/Zero #2 30 5h/Zero #1 30 5h/Zero #2 F53A3 1181 113 CIP1 closely related to cadmium-induced protein CIP1 21.63 2.88 1.71 16.67 12.33 11 12.14 4.67 1.33 3.07 0.283185841 0.078534031 0.141361257 0.92920354 0.554973822 1.911504425 1.397905759 0.318584071 0.073298429 0.486725664 0.136125654 0.761061947 3.415929204 1.329842932 0.247787611 0.212389381 0.041884817 0.203539823 0.068062827 0.539823009 0.10619469 0.052356021 0.10619469 0.062827225 0.168141593 0.104712042 0.504424779 0.183246073 J42B2 3690 689 PLB6 lysophospholipase B Lipid metabolism | Secreted/degradative enzymes | General metabolism 143.15 82.05 0.15 36.87 2.34 29 1.63 0.34 23.47 0.981802575 0.913304721 0.662145923 0.867639485 0.981802575 1.004635193 0.730643777 3.105236052 J16F1 3325 701 FRE8 ferric reductase Iron metabolism | Oxidoreductases 10.69 10.23 20.08 6.45 32.7 43.4 F23C12 1385 1302 hypothetical protein 1 1.57 0.98 2.09 4.07 10.17 6.94 3.65 4.97 7.85 4.923076923 4.897435897 2.615384615 3.435897436 F55E9 4883 1321 HWP1 hyphal wall protein Cell motility/budding/cell division | Cell wall components 3.32 1.77 1.23 9.63 95.76 75.58 25.04 47.5 69 21.5 89.39 63.5 116.78 75.5 71.21 34.63 63.80952381 80.32351692 65.76190476 88.50191137 43.80952381 59.87753079 16.95238095 28.04020954 34.9047619 81.7839445 21.14285714 36.51068951 18.38095238 23.95101232 2.095238095 9.346736514 40.23809524 45.85742602 23.80952381 42.06031431 13.23809524 22.19849922 2.761904762 26.57978196 3.761904762 7.302137902 2.238095238 7.010052386 1.095238095 5.257539289 0.19047619 1.46042758 Op1D8 4889 1327 RBT1 "repressed by Tup1, related to HWP1" Cell motility/budding/cell division | Cell wall components 3.02 30.02 22.01 100.9 58.62 57.03 215.86 35.14 165.37 2.197424893 12.93173759 1.665236052 2.675531915 1.493562232 1.337765957 1.175965665 1.449246454 2.412017167 1.296137339 0.9527897 0.969957082 2.954233156 7.141630901 19.06316489 1.957081545 1.184549356 2.731272163 1.356223176 3.991416309 1.56223176 1.278969957 2.452570922 F3C3 1935 1609 KRI1 Krr1p binding protein Miscellaneous 1.5 0.53 2.7 2 7.38 19.5 0.64 4 0.92 11.25 J14H2 1614 1816 ALS3 agglutinin-like protein Cell wall components 3.13 2.71 1.64 15.28 99.39 156.4 62.93 21.2 29.5 24.8 37.76 8 80.3 5.75 35.39 10.08 68.51851852 127.1666667 44 95.33333333 22.37037037 55.83333333 3.444444444 14.83333333 22.92592593 71.83333333 9.148148148 34 3.777777778 24.5 0.37037037 2.166666667 48.51851852 66.66666667 25 68.5 12 25.66666667 3.222222222 16.33333333 2.222222222 5 1.185185185 5.833333333 0.592592593 3.166666667 0.185185185 1 J28D7 7496 2059 Endonuclease/Exonuclease/phosphatase family 1.61 6.4 2.35 8.34 J23F5 7495 2060 SOD5 copper-zinc superoxide dismutase 0.56 0.63 0.36 0.8 2.99 12.03 8.27 17.57 12.21 16 1.13 0.71 3.62 0.5 1.52 2.15 11.4 15.11111111 4.68 8.111111111 1.68 4.777777778 1.08 1.111111111 3.2 5.888888889 0.96 2.111111111 1.08 1.444444444 0.52 1.111111111 5.36 7.666666667 3.8 4.111111111 2.16 4.444444444 0.76 3.666666667 1.24 2 0.88 1.888888889 0.68 1.444444444 0.64 1.333333333 F41B8 3574 2210 hypothetical protein 8.43 6 4.64 9.25 8.44 7 0.68 J5F3 1377 2355 ALS10 agglutinin-like protein Cell wall components 3.37 3.27 2.46 8.9 98.92 141.7 42.87 17.8 41.96 32.35 32.97 9 59.77 10.18 39.24 14.31 80.08333333 109.6923077 36.125 90.30769231 24.29166667 61.38461538 4.125 13.23076923 35.16666667 62.76923077 16.33333333 34.76923077 5.708333333 22.46153846 0.458333333 2.461538462 61.625 76.30769231 25.25 64.76923077 14.58333333 30.92307692 2.708333333 13.23076923 2.583333333 5.076923077 1.5 5.230769231 0.75 2.769230769 0.166666667 1.230769231 F68F6 7755 3018 conserved hypothetical protein DNA metabolism/repair | Transcription factors/chromatin/DNA-binding | General metabolism 2.98 4.24 1.09 8.25 11.08 8.11 4.67 4 4.86 10.06 4.56 14.23 2.38 20.21 6 0.382716049 0.727272727 0.139917695 0.4 0.106995885 0.36969697 0.12345679 0.43030303 0.172839506 0.098765432 0.357575758 0.102880658 0.275720165 0.094650206 0.028806584 0.024691358 0.086419753 0.032921811 0.290909091 0.020576132 0.181818182 0.028806584 0.2 0.197530864 0.242424242 F1E9 3199 3218 conserved hypothetical protein Unknown process and function 0.22 6.2 1.4 2.54 6.47 7.42 1 2 1.842105263 J5G4 2886 3374 ECE1 secreted cell elongation protein 8.24 6.95 4.22 21.07 67.73 65.61 46.73 9 8 7.85 53.49 78.47 7 91.15 43.15 483.5 627 202.5 351 69.75 161 9.25 29 249 225 61.75 160 24.25 27 0.75 2 202.75 156 66 113 39 62 6.25 26 3.25 5 1.75 4 1.25 2 0.5 1 Op1H3 7524 3829 PHR1 pH-regulated GPI-anchored membrane protein that is required for morphogenesis Miscellaneous 0.59 1.4 1.41 3.67 5.01 4.94 6.32 7.01 7.5 5.86 7.74 9.17 20.68852459 8.295081967 23.40532869 2.229508197 2.711041934 16.71809192 4.295081967 10.9345358 2 6.054660319 0.491803279 16.68852459 7.180327869 9.488646768 3.885826772 0.262295082 1.445889031 F55G1 2313 3852 "putative alpha-1,2-mannosidase" 2.53 9.9 9.7 11.05 17.91 10.4 7.16 9.9375 37.25 23.875 2.480769231 12 24.4375 12.625 17.25 0.615384615 0.480769231 J6H3 6854 4082 DDR48 flocculent specific protein | contains NNDDNSYG motif DNA metabolism/repair | Stress response | General metabolism 7.17 5.76 1.8 37.97 52.74 16.97 9 8.68 20.69 48.66 18 60.95 5.46 72.7 27.2 0.341317365 0.254545455 0.092814371 0.067532468 0.062874251 0.057142857 0.056886228 0.051948052 0.176646707 0.306493506 0.119760479 0.12987013 0.065868263 0.093506494 0.166233766 0.074850299 0.249350649 0.01497006 0.025974026 0.011976048 0.01038961 0.038922156 0.031168831 0.114285714 0.008982036 0.031168831 0.035928144 0.015584416 0.122754491 0.072727273 J5C9 4614 4309 GRP3 induced by osmotic stress Stress response | Oxidoreductases 3.52 3.92 1.83 16.83 9.96 3.63 25.92 11.48 14.27 0.847826087 0.32348367 1.413043478 0.616640747 1.565217391 0.384136858 1.434782609 1.108695652 1.695652174 0.444790047 1.739130435 0.369565217 0.131415241 0.891304348 1.5 5.173913043 0.391304348 0.111197512 0.782608696 0.212286159 1.5 4.282608696 0.950233281 J3G3 7905 4606 ERG8 phosphomevalonate kinase | involved in ergosterol biosyntesis pathway Lipid metabolism | General metabolism 1.02 1.33 3.02 7.63 4.85 5.57 7.37 F63B11 5799 4899 CGA1 "glycoamylase involved in beta 1,6-glucan synthesis | glucosidase II" ER/Golgi/secretion | Sugar/polysacchride metabolism | General metabolism 9.35 15.28 38.92 18.99 5.49 54.27 27.75 28.62 0.013580656 0.01623054 0.016893011 0.028486254 0.026498841 0.018549188 0.034448493 0.267969526 0.012255714 0.010930772 0.00960583 0.00662471 0.014243127 0.015236833 0.010930772 0.013911891 J26E5 5957 5141 hypothetical protein 12.35 2.35 7.86 4.13 F67B9 7697 5245 BUL4 ubiquitin ligase binding protein General metabolism 16.82 4.95 1.611111111 1.055555556 F67D2 8640 5404 HYR3 cell wall protein Cell wall components 0.8 1.19 1.12 5.3 11.94 0.55 1.02 J3G10 3624 5542 SAP6 candidapepsin 6 precursor Secreted/degradative enzymes | General metabolism 7.01 3.13 F49G2 3244 5567 POP4 rRNA and tRNA processing RNA metabolism | General metabolism 1.21 7.95 4.33 5.51 9.89 6.8 4.81 6.44 3.51 18.54545455 27.38888889 9.666666667 18.94444444 8.060606061 14.55555556 1.909090909 5 12.42424242 5.181818182 7.833333333 0.757575758 17.66666667 20.33333333 8.878787879 6.272727273 1.696969697 1.666666667 2.277777778 0.848484848 2.333333333 2 0.484848485 0.888888889 Op1G6 6893 5653 ATP2 "F1F0-ATPase complex, F1 beta subunit" Mitochondrial | General metabolism 102.13 49.03 19 55.88 24.49 10.78 1.631578947 68.61644598 0.715789474 37.36441527 0.494736842 24.64671192 0.347368421 6.901079337 2.547368421 30.46333593 16.56259041 0.442105263 12.8162902 1.478802715 31.6463781 1.252631579 33.12518082 10.05585846 0.757894737 3.056192278 1.084455324 M11B1 4915 5736 ALS5 agglutinin-like protein Unknown process and function 2.33 1.12 7.97 5.57 2.62 2.83 1.4875 0.6625 0.8375 2.125 1.5875 3.09375 M11A10 1115 5741 ALS1 agglutinin Cell wall components 0.44 1.07 0.97 0.85 14.02 2.23 1.32 14.17 15 1.92 4.02 3.02 25.67 2.68 31.14 2.975 0.775 1.2738 0.5 0.6948 0.2 0.2316 5.675 9.3798 0.5 1.9686 0.425 0.05 32.75 45.3936 8.925 10.422 2.825 7.527 0.75 55.575 42.3828 13.65 24.7812 5.35 5.9058 0.575 4.5162 F57G1 5094 6014 RRS1 regulator of ribosome synthesis RNA metabolism | General metabolism 1.06 0.47 1.45 5.5 8.79 4.69 3.41 7.91 16.90909091 33.59090909 31.72727273 18.63636364 7.454545455 18.77272727 23.95454545 8.318181818 8.954545455 15.68181818 27 2.772727273 15.22727273 14.72727273 17.40909091 12.04545455 J1A6 3156 6028 CLN2 G1 cyclin Cell cycle | Signaling/kinases/phosphatases 11.95 6.72 8.23 7.94 10.93 13.43 3.366935484 2.681451613 3.540322581 1.241935484 1.048387097 2.274193548 J8A6 7581 6037 conserved hypothetical protein 1.67 9.99 2.92 F63F5 5666 6148 USO2 intracellular protein transport ER/Golgi/secretion | General metabolism 1.04 18.33 4.05 4.07 8.04 10.5 7.76 17.88 5.45 8.66 4.61 5.23 J27G10 7834 6420 hypothetical membrane protein with repeated hydrophobic/hydrophilic domains Cell wall components 0.95 1.23 1.85 3.76 3.81 7.35 2.51 5.3 14.76 5.08 2.49 14.01 7.88 4.04 5.64 1.130434783 1.454545455 1.434782609 1.03030303 1.826086957 2.181818182 7.304347826 6.303030303 1 1.454545455 1.260869565 1.878787879 4.043478261 3.454545455 2.956521739 6.242424242 1.956521739 1.454545455 3.217391304 2.242424242 2.826086957 2.303030303 2.130434783 5.818181818 2.695652174 2.363636364 2.52173913 2.606060606 2.47826087 2.484848485 1 1.333333333 J14H6 8712 7460 conserved hypothetical protein Unknown process and function 3.83 4.27 7.2 13.29 4.91 4.83 F55E5 8898 7550 ORF MSV011 leucine rich repeat gene family protein 5.74 6.02 2.11 5.39 3.82 2.24 F28A6 2.34 9.62