UniqueID (Johnson lab) orf6 # orf19 # Name (Candida Annotation Working Group) Annotation (Candida Annotation Working Group) Gene class(es) nrg1/WT #1 nrg1/WT #2 nrg1/WT #3 nrg1/WT #4 nrg1/WT #5 nrg1/WT #6 F11C12 3443 1166 conserved hypothetical protein ER/Golgi/secretion 0.46 0.48 0.51 0.71 0.61 0.45 M15H9 5154 220 PIR1 cell wall structural constituent with tandem repeats Cell wall components 0.25 0.51 0.19 0.46 0.15 0.1 F55A1 4202 2350 "highly conserved hypothetical protein, MFS family transporter" Unknown process and function 0.4 0.32 0.38 F63D1 6587 2765 hypothetical protein Cell wall components 0.23 0.72 0.25 0.27 0.46 0.19 F59H3 3268 2862 RIB1 "GTP cyclohydrolase II, first step in riboflavin biosynthesis" General metabolism 0.67 0.56 0.43 J16C2 7803 3066 ACF3 "endo-1,3-beta-glucanase" Secreted/degradative enzymes | Cell wall components | Sugar/polysacchride metabolism 0.23 0.53 0.25 0.18 0.29 0.25 J31H7 1590 3071 MIH1 protein tyrosine phosphatase Cell cycle | Signaling/kinases/phosphatases 0.55 0.4 0.53 0.47 0.53 F9B7 4481 3184 SFT2b similar to syntaxin and involved in ER to Golgi transport ER/Golgi/secretion 0.32 0.39 0.65 0.46 F53E9 3288 3618 YWP1 putative cell wall protein Cell wall components 0.03 0.02 0.04 0.07 0.11 0.09 F12B8 1866 3803 MNN22 "Golgi alpha-1,2- mannosyltransferase" ER/Golgi/secretion | Sugar/polysacchride metabolism | General metabolism 0.61 0.44 0.33 0.29 0.5 0.4 J42E8 550 3869 hypothetical protein 0.33 0.35 0.2 0.14 0.39 0.6 J17C10 5845 3874 hypothetical protein 0.46 0.44 0.63 0.46 0.47 0.59 F12G12 2346 3893 SCW11 Soluble Cell Wall protein Cell wall components | Sugar/polysacchride metabolism 0.08 0.35 0.07 0.09 0.1 0.13 F21C3 5137 3911 SAH1 S-adenosyl-L-homocysteine hydrolase Amino acid biosynthesis/metabolism/transport | General metabolism 0.45 0.45 0.36 0.37 0.43 0.46 F36B10 2095 412 SSH1 involved in co-translational pathway of protein transport ER/Golgi/secretion | General metabolism 0.38 0.58 0.45 0.61 0.38 0.53 F53E5 2516 4127 SH3 domain protein with a putative role in the regulation of the actin cytoskeleton Cell motility/budding/cell division | ER/Golgi/secretion 0.41 0.47 0.38 0.67 0.55 0.53 M15D8 7251 4438 RME1 zinc-finger transcription factor 0.23 0.15 0.42 0.21 0.22 F50A6 3754 4907 conserved hypothetical protein Unknown process and function 0.21 0.54 0.15 0.44 0.44 0.15 F14A1 3757 4910 hypothetical protein Cell wall components 0.05 0.14 0.05 0.05 0.04 0.03 J1F3 2433 4950 AKR1 ankyrin repeat-containing protein ER/Golgi/secretion | Signaling/kinases/phosphatases | General metabolism 0.71 0.67 0.65 0.57 0.59 0.68 J10F1 7977 5032 SIM1 protein invovled in control of DNA replication Cell wall components | Mitochondrial 0.35 0.62 0.43 0.47 0.34 0.52 F59A2 6305 5071 NRP1 "RNA-binding, Ran zinc finger protein" Unknown process and function 0.54 0.45 0.5 0.55 0.63 0.45 J17E10 6972 5164 ECM39 "alpha-1,6- mannosyltransferase" ER/Golgi/secretion | Sugar/polysacchride metabolism | General metabolism 0.57 0.49 0.6 0.65 0.53 0.59 F44B9 7675 5267 conserved hypothetical protein 0.08 0.47 0.15 0.12 0.11 0.06 J9G7 5127 6229 CTA1 "catalase A, peroxisomal" Oxidoreductases | General metabolism 0.5 0.79 0.53 0.5 0.5 F62A8 7558 6570 NUP3 purine nucleoside permease 0.33 0.39 0.23 0.24 0.24 F66A6 6542 6645 HMO1 high mobility group-like protein Transcription factors/chromatin/DNA-binding | Cell cycle 0.45 0.35 0.3 0.36 0.38 Op1B11 8814 6817 FCR1 zinc finger transcription factor involved in pleiotropic drug resistance 0.2 0.1 0.19 F59E2 8807 6824 conserved hypothetical protein containing Helix-loop-helix DNA-binding domain 0.72 0.5 0.38 F44F5 7138 6874 myb-like transcription factor Transcription factors/chromatin/DNA-binding | Amino acid biosynthesis/metabolism/transport | General metabolism 0.38 0.54 0.44 0.5 0.75 0.39 F14C9 8118 7218 PRY2 homology to plant PR-1 class of proteins Secreted/degradative enzymes | Vacuolar 0.13 0.17 0.06 0.04 0.03 J28H1 8606 7446 OPI3 methylene-fatty-acyl-phospholipid synthase Lipid metabolism | ER/Golgi/secretion | General metabolism 0.21 0.41 0.35 0.47 0.49 F54G5 4136 747 NBP35 nuclear ATPase Miscellaneous 0.54 0.55 0.46 0.58 0.57 F69C3 8902 7554 SGE1 suppressor of gal11 null Miscellaneous 0.48 0.45 0.48 0.36 0.36 F69E4 8934 7586 CHT3 chitinase 3 precursor ER/Golgi/secretion | Secreted/degradative enzymes | Cell wall components | Sugar/polysacchride metabolism 0.08 0.21 0.08 0.03 0.09 0.09 M15G4 6705 814 SSY1.5 transcriptional regulator of multiple amino acid permeases Miscellaneous 0.29 0.63 0.2 J9E10 5814 984 PHO82 vacuolar alkaline phosphatase Transcription factors/chromatin/DNA-binding | DNA metabolism/repair | Vacuolar | General metabolism 0.59 0.58 0.71 0.67 0.63 0.59 SAM False Discovery Rate (FDR) = 0.52%