UniqueID (Johnson lab) orf6 # orf19 # Name (Candida Annotation Working Group) Annotation (Candida Annotation Working Group) Gene class(es) tup1/WT #1 tup1/WT #2 tup1/WT #3 tup1/WT #4 tup1/WT #5 tup1/WT #6 F66G5 2846 1193 GNP2 high-affinity glutamine permease Amino acid biosynthesis/metabolism/transport 0.49 0.25 0.38 0.25 0.20 F51F4 332 1357 FCY2 purine-cytosine permease Miscellaneous 0.34 0.41 0.52 0.41 0.42 J33D2 7098 1474 SLA1 SH3 domain protein involved in cortical actin cytoskeleton Cell motility/budding/cell division | ER/Golgi/secretion 0.43 0.26 0.39 0.39 F30E1 1885 1573 ATC9 cation translocating P-type ATPase Unknown process and function 0.42 0.46 0.24 0.4 J12D9 1090 1614 MEP3 low affinity high capacity ammonium permease Miscellaneous 0.52 0.26 0.13 0.21 0.12 F49C2 2231 1799 GAP6 general amino acid permease Amino acid biosynthesis/metabolism/transport 0.56 0.18 0.39 0.36 0.37 0.35 J33D6 5615 1847 ARO10 putative decarboxylase Amino acid biosynthesis/metabolism/transport | General metabolism 0.12 0.10 0.5 0.08 0.14 0.36 F61G2 6363 1996 CHA2 catabolic serine/threonine dehydratase Amino acid biosynthesis/metabolism/transport | Mitochondrial | General metabolism 0.26 0.39 0.46 0.18 0.31 0.35 J3A3 7486 2069 SMF3 vacuolar metal transporter Iron metabolism | Vacuolar 0.51 0.37 0.26 0.42 0.16 M4D5 5571 2337 ALP1 high-affinity permease for basic amino acids Amino acid biosynthesis/metabolism/transport 0.1 0.32 0.14 0.06 0.22 0.15 F63C5 3372 2525 LYS12 homo- isocitrate dehydrogenase Amino acid biosynthesis/metabolism/transport | Oxidoreductases | Mitochondrial | General metabolism 0.5 0.54 0.62 0.44 0.38 0.52 J31H3 3590 2758 "hypothetical protein, similar to RBT1" Cell wall components 0.2 0.28 0.57 0.27 0.38 0.42 F56G5 713 3195 GAP3 general amino acid permease Amino acid biosynthesis/metabolism/transport 0.29 0.42 0.43 0.19 0.36 0.17 F53E9 3288 3618 YWP1 putative cell wall protein Cell wall components 0.1 0.05 0.13 0.10 0.18 0.13 F21C3 5137 3911 SAH1 S-adenosyl-L-homocysteine hydrolase Amino acid biosynthesis/metabolism/transport | General metabolism 0.32 0.29 0.39 0.45 0.31 0.66 J17D7 804 4118 NNT1 concentrative Na+-nucleoside cotransporter 0.24 0.55 0.37 0.31 0.44 0.36 J31G8 4607 4304 GAP1 general amino acid permease Amino acid biosynthesis/metabolism/transport 0.48 0.28 0.43 0.46 0.31 0.19 F24F12 3152 4716 GDH3 NADP-glutamate dehydrogenase Amino acid biosynthesis/metabolism/transport | Oxidoreductases | General metabolism 0.2 0.20 0.16 0.04 0.18 0.09 F50A6 3754 4907 conserved hypothetical protein Unknown process and function 0.18 0.34 0.38 0.53 0.16 0.16 F14A1 3757 4910 hypothetical protein Cell wall components 0.26 0.28 0.37 0.28 0.21 0.32 F10D3 6958 5178 ERG5 cytochrome P450 Lipid metabolism | ER/Golgi/secretion | General metabolism 0.37 0.36 0.29 0.47 F1B3 3409 5193 benzil reductase Unknown process and function 0.01 0.01 0.04 0.01 0.01 0.01 F44B9 7675 5267 conserved hypothetical protein 0.19 0.22 0.77 0.19 0.25 0.23 F31H9 4661 5496 transmembrane amino acid transporter Amino acid biosynthesis/metabolism/transport | Vacuolar 0.34 0.45 0.31 0.39 F14C3 1361 5572 VAN2 mannosyltransferase: vanadate resistance protein 0.54 0.56 0.41 0.49 0.47 J37A9 6542 6645 HMO1 high mobility group-like protein Transcription factors/chromatin/DNA-binding | Cell cycle 0.36 0.63 0.4 0.52 0.36 0.40 J46C2 6764 6656 DUR8 urea transport protein 0.31 0.38 0.26 0.35 0.37 0.33 F44E5 7323 6937 PTR2 peptide transporter Miscellaneous 0.58 0.09 0.23 0.21 0.13 0.16 F35C1 8366 7285 conserved hypothetical protein Transcription factors/chromatin/DNA-binding | RNA metabolism | General metabolism 0.42 0.61 0.51 0.47 0.52 M4G10 8420 7339 BGL1 beta-glucosidase 2 precursor 0.33 0.39 0.62 0.42 0.40 J44D5 8590 7433 NUP116 nuclear pore protein | nucleoporin RNA metabolism | General metabolism 0.35 0.56 0.42 0.33 J28H1 8606 7446 OPI3 methylene-fatty-acyl-phospholipid synthase Lipid metabolism | ER/Golgi/secretion | General metabolism 0.23 0.42 0.37 0.4 0.29 J17G2 8902 7554 SGE1 suppressor of gal11 null Miscellaneous 0.21 0.31 0.22 0.27 0.20 J12D2 8934 7586 CHT3 chitinase 3 precursor ER/Golgi/secretion | Secreted/degradative enzymes | Cell wall components | Sugar/polysacchride metabolism 0.08 0.31 0.18 0.09 0.11 0.24 F48H5 9003 7655 RPO21 "DNA-directed RNA polymerase II, 215 KD subunit" Transcription factors/chromatin/DNA-binding | General metabolism 0.21 0.33 0.38 0.41 F52E3 2989 789 PYC2 pyruvate carboxylase Sugar/polysacchride metabolism | General metabolism 0.23 0.16 0.18 0.57 J36B4 no orf6 4623.3 NHP6A non-histone protein similar to high mobility group proteins DNA metabolism/repair | Transcription factors/chromatin/DNA-binding | General metabolism 0.22 0.17 0.36 0.26 0.43 0.29 SAM False Discovery Rate (FDR) = 0.18%