References Added to CGD in the past week, since 2024-12-14

Newly curated references since 2024-12-14

Reference

Species

Genes Addressed

Carolus H, et al. (2024) Acquired amphotericin B resistance leads to fitness trade-offs that can be mitigated by compensatory evolution in Candida auris. Nat Microbiol

C. auris

|B9J08_000341 |CDC25 |CLD1 |ERG10 |ERG11 |ERG12 |ERG3 |ERG6 |HMG1 |HRR25 |MAL31 |NCP1 |SLY41

Chen R, et al. (2024) DNA damage repair factor Rad18 controls virulence partially via transcriptional suppression of genes HWP1 and ECE1 in Candida albicans. Virulence :2433201

C. albicans

|ALD6 |ALS4 |AMO1 |CAP1 |ECE1 |HGT17 |HGT2 |HPD1 |HWP1 |JEN2 |PHO84 |PLB1 |RAD18 |RBR3

Conway TP, et al. (2024) Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs. mSphere :e0079224

C. glabrata

|BRE5 |CDR1 |CNA1 |CRZ1 |ERG11 |ERG4 |GAL11A |PDR1 |UPC2A

Fang T, et al. (2024) Extracellular Hsp90 of Candida albicans contributes to the virulence of the pathogen by activating the NF-kappaB signaling pathway and inducing macrophage pyroptosis. Microbiol Res 290:127964

C. albicans

|HSP90 |PRB1

Goncalves B, et al. (2024) Biofilm matrix regulation by Candida glabrata Zap1 under acidic conditions: transcriptomic and proteomic analyses. Microbiol Spectr :e0120124

C. glabrata

|ZAP1

Karakoyun AS, et al. (2024) Integrating Clinical and Microbiological Expertise to Improve Vaginal Candidiasis Management. Mycopathologia 189(6):96

Kuplinska A, et al. (2024) Targeting Candida albicans O-acetyl-L-homoserine sulfhydrylase (Met15p) in antifungal treatment. Sci Rep 14(1):28188

C. albicans

|MET15

Patel NK, et al. (2024) Converging Roles of the Metal Transporter SMF11 and the Ferric Reductase FRE1 in Iron Homeostasis of Candida albicans. Mol Microbiol

C. albicans

|CFL1 |CFL11 |CFL2 |FRE10 |FRP1 |SMF11 |SMF12 |SMF13

Wang WH, et al. (2024) Transcriptional profiling reveals the role of Candida albicans Rap1 in oxidative stress response. Biosci Rep

C. albicans

|CAP1 |HOG1 |RAP1 |RPS6A |SOD1 |SOD2 |SOD3 |SOD4 |SOD5 |TOR1

Zhang CW, et al. (2024) The Antifungal Effects of Berberine and Its Proposed Mechanism of Action Through CYP51 Inhibition, as Predicted by Molecular Docking and Binding Analysis. Molecules 29(21)

C. albicans

|ERG11

Zhang G, et al. (2024) Association of multilocus sequence typing, MSH2 gene mutations, and antifungal resistance in Candida glabrata: implications for clinical outcomes in Chinese hospitals. Ann Clin Microbiol Antimicrob 23(1):100

C. glabrata

|MSH2

References automatically added to CGD since 2024-12-14
(possibly not yet curated)

Reference

Species

Genes Addressed

Dishan A, et al. (2025) Candida species covered from traditional cheeses: Characterization of C. albicans regarding virulence factors, biofilm formation, caseinase activity, antifungal resistance and phylogeny. Food Microbiol 127:104679

C. albicans

|ERG11 |GSC1 |GSL1 |HSP90 |PLB1

Jimenez EJM, et al. (2025) Self-induced anaerobiosis fermentation in coffees inoculated with yeast: Effect on key enzymes of the germination process and its relationship with the decrease in seed germination. Food Res Int 199:115376

C. parapsilosis

|ADH

Bednarek A, et al. (2024) Exploring the effects of culture conditions on Yapsin (YPS) gene expression in Nakaseomyces glabratus. Open Life Sci 19(1):20220995

C. glabrata

|YPS1 |YPS11 |YPS6 |YPS7

Goich D, et al. (2024) Gcn2 rescues reprogramming in the absence of Hog1/p38 signaling in C. neoformans during thermal stress. mBio :e0176224

C. albicans

|GCN2 |HOG1

Gupta T, et al. (2024) Assessment of Bioactivity of Homalomena aromatica Essential Oil From Northeast India Through Combinative In Vitro and In Silico Approaches. Chem Biodivers :e202402254

C. albicans

|COX2 |CYP5 |ERG11

He X, et al. (2024) Candida albicans-Derived beta-Glucan as a Novel Modulator of Tumor Microenvironment: Targeting Macrophage Polarization and Inducing Ferroptosis in Lung Cancer. J Inflamm Res 17:10479-10494

C. albicans

|GPX3

Liu M, et al. (2024) Evaluation and Comparison of Candida albicans vs Mammalian 6-O-Phospho-Kinases: Substrate Specificity and Applications. Biochemistry

C. albicans

|HXK1

Tikent A, et al. (2024) Antioxidant potential, antimicrobial activity, polyphenol profile analysis, and cytotoxicity against breast cancer cell lines of hydro-ethanolic extracts of leaves of (Ficus carica L.) from Eastern Morocco. Front Chem 12:1505473

C. albicans

|CYP5 |ERG11

Zhang D, et al. (2024) Different fungal signatures in ALD and MAFLD. Front Microbiol 15:1510507

C. albicans

|ITS2

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To cite CGD, please use the following reference: Skrzypek MS, Binkley J, Binkley G, Miyasato SR, Simison M, Sherlock G (2017). The Candida Genome Database (CGD): incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data. Nucleic Acids Res 45 (D1); D592-D596; see How to cite CGD.