References Added to CGD in the past week, since 2026-01-26

Newly curated references since 2026-01-26

Reference

Species

Genes Addressed

Batista CSP, et al. (2025) Community-Onset Fungemias: Epidemiology and Genomic Characterization at a Tertiary-Care Hospital in Barcelona, Spain. J Fungi (Basel) 11(11)

C. albicans

|CDR1 |ERG11 |MRR1 |MRR2

C. glabrata

|ERG2 |FKS2 |PDH1 |PDR1

De Luca DG, et al. (2025) Phylogenomic analysis and genetic mechanisms of antifungal resistance in clinical isolates of Candida glabrata (Nakaseomyces glabratus) from across Canada, 2013-2020. Microbiol Spectr :e0180325

C. glabrata

|CDR1 |ERG11 |FKS1 |FKS2 |PDH1 |PDR1 |SNQ2 |UPC2A

Dostal J, et al. (2025) Structural characterization and inhibition of carbonic anhydrase from Candida parapsilosis. J Struct Biol X 12:100140

C. parapsilosis

|NCE103

C. albicans

|NCE103

Gruber D, et al. (2025) Amyloid fibrils of the Als5p-derived peptide NH(2)-SNGIVIVATTRTV-COOH influence the biofilm formation of Candida albicans by shape-edging microcolony morphology. Virulence 16(1):2597576

C. albicans

|ALS5

Harrington AA, et al. (2025) Echinocandin tolerance and persistence in vitro are regulated by calcineurin signaling in Candida glabrata. mBio :e0254625

C. glabrata

|CNA1 |CNB1 |CRZ1 |FKS1 |GTB1 |HOG1 |IPT1 |PBS2

Krishnan CS, et al. (2025) Molecular Mechanism of Action of HOCl from Neutral-pH Electrolysed Oxidising Water Against Candida albicans. J Fungi (Basel) 11(11)

C. albicans

|ATO2 |BIO5 |EBP1 |GAP5 |GAP6 |HSP21 |IRE1 |PRN1 |STP4 |SUT1

Orsud H, et al. (2025) Multi-marker comparative analysis of 18S, ITS1, and ITS2 primers for human gut mycobiome profiling. Front Bioinform 5:1690766

C. albicans

|ITS1 |ITS2

Vindu A, et al. (2025) Combined inhibition of polyamine biosynthesis and uptake blocks Candida albicans virulence. mBio :e0352425

C. albicans

|HOL1 |HOL2 |SPE1

Zhao Q, et al. (2025) Mitochondrial complex III subunit Qcr8 regulates the virulence and adhesion of Candida albicans by modulating mitochondrial function. Microbiol Spectr :e0167225

C. albicans

|CYR1 |EFG1 |FLO8 |QCR7 |QCR8 |RAS1 |TPK1 |TPK2

de Freitas IO, et al. (2025) FLA94, an isatin derivative, inhibits Candida albicans growth by inducing membrane damage and ROS overaccumulation. Future Microbiol :1-14

C. albicans

|ALS3 |SAP2

References automatically added to CGD since 2026-01-26
(possibly not yet curated)

Reference

Species

Genes Addressed

Belgacem S, et al. (2026) In vitro Susceptibilities to caspofungin of Candida spp. isolated from the Polyvalent Intensive Care Unit of Fattouma Bourguiba University Hospital: First report of resistant mutants in Tunisia. J Mycol Med 36(1):101601

C. glabrata

|FKS1

C. albicans

|GSC1 |GSL1

Bolsenbroek A, et al. (2026) The role of OLE2 and POX1-3 in prostaglandin E(2) production and virulence is conserved in Candidozyma (Candida) auris. Microbiol Spectr :e0232325

C. albicans

|OLE2 |POX1 |POX1-3

C. dubliniensis

|Cd36_81950

Davis FA and O'Meara TR (2026) Microbial interactions: Crosstalk in the fungal mycobiome through a novel small protein. Curr Biol 36(1):R25-R27

C. glabrata

|YHI1

Davis FA, et al. (2026) Bacterial metabolites induce cell wall remodeling, antifungal resistance, and immune recognition of commensal fungi. Curr Biol

C. albicans

|SLN1

Elekhnawy E, et al. (2026) Antifungal activity of oily core PEGylated PLGA nanocapsules loaded with Penicillium oxalicum fungal extract: in vitro, in vivo, and in silico study. Microb Cell Fact

C. albicans

|SAP4

Hou J and Li M (2026) MiR-210 suppresses Candida albicans-derived beta-glucan-induced inflammation in THP-1-derived macrophages via the Syk-NF-kappaB pathway. Immunobiology 231(1):153156

C. albicans

|C1_11910W_A

Jayasekara LACB, et al. (2026) Overcoming Candida albicans biofilm drug resistance via azole-sophorolipid synergy. Sci Rep

C. albicans

|BCR1 |CDC28 |EFG1

Khan N and Faryal R (2026) Emerging role of Candida species virulence factors and antifungal resistance in ureteral stent colonization and encrustation. Acta Trop 274:107979

C. albicans

|ALS1 |ERG11 |HWP1

Lanser DM, et al. (2026) Conjugation of a Cryptococcus neoformans-derived metalloprotease to antifungal-loaded PLGA nanoparticles treats neural cryptococcosis in an in vitro model. PLoS One 21(1):e0340202

C. albicans

|RPN11

Lee S, et al. (2026) Genomic Insights into Candidozyma auris Clade II: Comparative Phylogenomics and Structural Validation of Fluconazole Resistance Mechanisms. J Fungi (Basel) 12(1)

C. auris

|TAC1b

Lok B, et al. (2026) Gene expression profiling of the carbon pathways and virulence factors of Candida albicans in different carbon sources. Microb Pathog 212:108311

C. albicans

|ICL1 |MDH1 |MDH1-1 |MLS1

Lortal L, et al. (2026) Candida albicans-induced ubiquitination of EGFR reveals novel host-fungal interaction pathways. mBio :e0344825

C. albicans

|ALS3 |ECE1

Ma S-J, et al. (2026) Non-receptor tyrosine kinase c-Abl downstream of C-type lectin receptors regulates innate antifungal immunity through c-Cbl/MAPK pathway. Infect Immun :e0036525

C. albicans

|CEK1

Martinez M, et al. (2026) C. elegans as a tractable infection model for the emerging fungal pathogen Candida auris. Microbiol Spectr :e0315625

C. albicans

|ADE2

Mundhe AK, et al. (2026) In silico screening of IMPPAT-derived phytochemicals targeting ERG6 and drug resistance-associated proteins in drug-resistant Candida albicans: virtual screening and molecular dynamics using alphafold models. In Silico Pharmacol 14(1):30

C. albicans

|CDR1 |CDR11 |CDR2 |CLB2 |ERG1 |ERG11 |ERG6

Neves BR, et al. (2026) Adherence assessment of Candida albicans on CAD/CAM and conventional resin for denture base: A systematic review and network meta-analysis. J Prosthodont Res

C. albicans

|ADH1

Nouayti FZ, et al. (2026) Synthesis, Characterization, Density Functional Theory Calculation, In Silico and In Vitro Antimicrobial Evaluation of New 1,2,4-Triazole-Amide Conjugates. Chem Biodivers 23(1):e03349

C. albicans

|CYP5 |ERG11

O'Connor-Moneley J, et al. (2026) Depletion of the Candida albicans TLO gene family reveals a requirement for alpha TLO genes for wild-type virulence. Microbiology (Reading) 172(1)

C. albicans

|CTA26 |TLO5

Pedras A, et al. (2026) The siderophore transporter Sit1 is involved in the uptake of caspofungin by Candida albicans. Antimicrob Agents Chemother :e0123625

C. albicans

|SIT1

Piraine REA, et al. (2026) Fungal extracellular vesicles mediate conserved cross-species communication and immunomodulation. mBio :e0346925

C. auris

|ERG11

C. albicans

|ERG11 |LAC1

Sadiq GM, et al. (2026) Phenylpiperazine/dithioates as novel H(2)S donors: design, synthesis, H(2)S release, formulation as PEG-niosomes and antifungal activity against Candida albicans. Bioorg Chem 170:109494

C. albicans

|CYP5 |ERG11

Spera AM, et al. (2026) Nine-Year Surveillance of Candida Bloodstream Infections in a Southern Italian Tertiary Hospital: Species Distribution, Antifungal Resistance, and Stewardship Implications. J Pers Med 16(1)

C. albicans

|C1_14510C_A |C4_03220C_A |C4_03260C_A |C7_04350C_A

Sze JLJ, et al. (2026) Fungal Reactive Oxygen Species Secreted by Candida albicans Induce Barrier Disruption and Cell Death in HaCaT Keratinocytes. J Fungi (Basel) 12(1)

C. albicans

|C1_11020W_A |CFL11

Toth Hervay N, et al. (2026) Catechin Augments the Antifungal Efficacy of Fluconazole Against Candida parapsilosis. Int J Mol Sci 27(2)

C. parapsilosis

|CDR1B |TAC1

Tuan DA and Masak J (2026) Ocimum gratissimum (Linnaeus) essential oil disrupts Candida albicans biofilms via morphogenetic suppression and stress reprogramming: translational implications for antifungal prophylaxis. Biofouling :1-14

C. albicans

|ALS3 |BCR1 |CSR1 |EFG1 |GSC1 |GSL1 |HSP90 |HWP1 |SOD5

Wang Y (2026) Mechanistic insights into Gwt1-substrate interactions and antifungal drug discovery via molecular dynamics and virtual screening. J Biomol Struct Dyn :1-9

C. albicans

|GWT1

Wei Y and Mao X (2026) Vacuole and mitochondria patch (vCLAMP) protein Mcp1 reduces the pathogenesis of Candida albicans by impeding the function of Cap1-mediated oxidative stress response. BMC Microbiol

C. albicans

|CAP1 |GLR1 |MCP1 |SOD2 |SRV2 |TRR1

Wei Y, et al. (2026) Candida albicans Extracellular Vesicles Upregulate Nrg1 Transcription Repressor to Inhibit Self-Hyphal Development and Candidemia. Int J Mol Sci 27(1)

C. albicans

|BRG1 |C3_06690C_A |NRG1 |SKO1

Wei Y, et al. (2026) Controllable Engineered Probiotic Hydrogel Coatings Prevent Drainage Tube-Associated Infections by Disrupting Pathogen Oxidative Stress Responses. Adv Healthc Mater :e05654

C. albicans

|ARO10

Zabad G, et al. (2026) Antifungal efficacy of Miswak extracts versus sodium hypochlorite against Candida albicans on CAD-CAM denture base: an in-vitro study. BMC Complement Med Ther

C. albicans

|ADH1

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To cite CGD, please use the following reference: Skrzypek MS, Binkley J, Binkley G, Miyasato SR, Simison M, Sherlock G (2017). The Candida Genome Database (CGD): incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data. Nucleic Acids Res 45 (D1); D592-D596; see How to cite CGD.