Genome-wide Analysis papers

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Genome-wide AnalysisProteome-wide Analysis
Comparative genomic hybridizationLarge-scale protein detection
Computational analysisLarge-scale protein interaction
Genomic co-immunoprecipitation studyLarge-scale protein localization
Genomic expression studyLarge-scale protein modification
Large-scale genetic interactionOther large-scale proteomic analysis
Large-scale phenotype analysis 
Other genomic analysis 

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ReferenceLiterature TopicSpeciesGenes Addressed
Allert S, et al. (2018) Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers. MBio 9(3)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale phenotype analysisC. albicans |AAF1 |ALS3 |BAS1 |C1_01490W_A |C1_07480C_A |CPH1 |DEF1 |ECE1 |HGC1 |HMA1 |KEX1 |NPR2 |PEP12 |SAP1 |MORE
Awad A, et al. (2018) Proteomic analysis of a Candida albicans pga1 Null Strain. EuPA Open Proteom 18:1-6
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |APE2 |CDC11 |CDR1 |CDR2 |CFL1 |CR_03530W_A |EGD2 |ERG1 |ERG11 |EXG2 |HSP70 |HSP90 |INT1 |LIP10 |MORE
Awad A, et al. (2018) Tandem Mass Spectrometric Cell Wall Proteome Profiling of a Candida albicans hwp2 Mutant Strain. Curr Mol Pharmacol 11(3):211-225
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |CHT2 |HWP2 |MTS1 |PGA28 |PGA32 |PGA41 |PGA50 |PHR1 |RBR1 |SAP10 |SAP4 |SAP5
Caplan T, et al. (2018) Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans. Cell Rep 23(8):2292-2298
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Large-scale phenotype analysisC. albicans |AHR1 |BCK1 |C6_00530C_A |CAS5 |CAT1 |CCT8 |DBP8 |GSC1 |GSL1 |HSP90 |KEX2 |MKC1 |NOP14 |PKC1 |MORE
Chen Y, et al. (2018) Chemogenomic Profiling of the Fungal Pathogen Candida albicans. Antimicrob Agents Chemother 62(2)
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Large-scale phenotype analysisC. albicans |ADP1 |AGM1 |ALO1 |C1_07050C_A |C1_10320W_A |C1_14500C_A |C2_05290C_A |C3_03110W_A |C4_00470C_A |C4_04870C_A |C5_00560W_A |C6_00430C_A |C6_02410W_A |CHS7 |MORE
El Khoury P, et al. (2018) Proteomic analysis of a Candida albicans pir32 null strain reveals proteins involved in adhesion, filamentation and virulence. PLoS One 13(3):e0194403
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Large-scale protein detectionC. albicans |ALS3 |CDC42 |CSA2 |DCW1 |DFG5 |PIR32 |RBT5 |SSR1 |SSU81 |UCF1 |XOG1
Forche A, et al. (2018) Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans. Genetics 209(3):725-741
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. albicans |GAL1
Herrero-de-Dios C, et al. (2018) Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs. MBio 9(2)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |HOG1
Huang M and Kao KC (2018) Identifying novel genetic determinants for oxidative stress tolerance in Candida glabrata via adaptive laboratory evolution. Yeast 35(11):605-618
CGD Papers Entry  Pubmed Entry  
Large-scale phenotype analysisC. glabrata |CAGL0C00385g |CAGL0F06831g |CTH2
Jiang L, et al. (2018) CaGdt1 plays a compensatory role for the calcium pump CaPmr1 in the regulation of calcium signaling and cell wall integrity signaling in Candida albicans. Cell Commun Signal 16(1):33
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |C5_05020C_A |CEK1 |CHS2 |CHS3 |CHS8 |DIE2 |GDT1 |MKC1 |PMR1 |PMT1 |PMT4 |STT3 |SWI4
Kaneva IN, et al. (2018) Quantitative Proteomic Analysis in Candida albicans Using SILAC-Based Mass Spectrometry. Proteomics 18(5-6):e1700278
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |ARG4 |CDC14
Lee JH, et al. (2018) Antibiofilm and Antivirulence Activities of 6-Gingerol and 6-Shogaol Against Candida albicans Due to Hyphal Inhibition. Front Cell Infect Microbiol 8:299
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |CDR1 |CDR2 |ECE1 |HWP1 |RTA3
McCall AD, et al. (2018) Candida albicans Sfl1/Sfl2 regulatory network drives the formation of pathogenic microcolonies. PLoS Pathog 14(9):e1007316
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Genomic expression studyC. albicans |ECE1 |HWP1 |HYR1 |IHD1 |NDT80 |PGA10 |PLB1 |ROB1 |SAP5 |SFL1 |SFL2
Mount HO, et al. (2018) Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. PLoS Genet 14(4):e1007319
CGD Papers Entry  Pubmed Entry  
Large-scale genetic interaction, Large-scale phenotype analysisC. albicans |APM1 |CR_03430W_A |ERG3 |ERG5 |GZF3 |KIC1 |MRR2 |NPR2 |PBS2 |PEP8 |RCY1 |RGD1 |SET6 |SSK2 |MORE
Nair R, et al. (2018) Identification of genome-wide binding sites of heat shock factor 1, Hsf1, under basal conditions in the human pathogenic yeast, Candida albicans. AMB Express 8(1):116
CGD Papers Entry  Pubmed Entry  
Genomic co-immunoprecipitation studyC. albicans |CTA8
O'Meara TR, et al. (2018) High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis. MBio 9(4)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale phenotype analysisC. albicans |HOG1 |MNN2 |MNN21 |MNN22 |MNN23 |MNN24 |MNN26 |PGA52
Schoeters F, et al. (2018) A High-Throughput Candida albicans Two-Hybrid System. mSphere 3(4)
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Large-scale protein interactionC. albicans |PCL5 |PHO85
Segal ES, et al. (2018) Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans. MBio 9(5)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale phenotype analysisC. albicans |ASK1 |C1_12660W_A |C1_12810W_A |C2_06230W_A |C6_04120C_A |C7_02460C_A |CDC11 |CDC12 |CDC3 |CLN3 |CR_03740C_A |CR_05100W_A |FAD1 |KRR1 |MORE
Thakre A, et al. (2018) Limonene inhibits Candida albicans growth by inducing apoptosis. Med Mycol 56(5):565-578
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |C6_02480W_A |CCT8 |CRN1 |CR_04650W_A |EBP1 |KRE6 |MBF1 |NPL3 |PIL1 |PIN3 |RHR2 |RPL11 |RPL15A |RPL29 |MORE
Tripathi H and Khan F (2018) Identification of potential inhibitors against nuclear Dam1 complex subunit Ask1 of Candida albicans using virtual screening and MD simulations. Comput Biol Chem 72:33-44
CGD Papers Entry  Pubmed Entry  
Computational analysisC. albicans |ASK1 |DAM1
Tucey TM, et al. (2018) Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection. Cell Metab 27(5):988-1006.e7
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |GAL4 |TYE7
Turner SA, et al. (2018) Dal81 Regulates Expression of Arginine Metabolism Genes in Candida parapsilosis. mSphere 3(2)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. parapsilosis |DAL81 |GAT1 |GCN4 |GZF3 |PUT3 |UGA3
Uppuluri P, et al. (2018) Candida albicans Dispersed Cells Are Developmentally Distinct from Biofilm and Planktonic Cells. MBio 9(4)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |ACE2 |ARO2 |ARO3 |ARO4 |ARO8 |ARO9 |ASC1 |CDC5 |CHA1 |CHS1 |CHS2 |CHS8 |CHT1 |CHT2 |MORE
Veri AO, et al. (2018) Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space. PLoS Genet 14(3):e1007270
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |ACT1 |AHA1 |BRG1 |BUB2 |C5_05270C_A |CDC37 |CPR6 |CTA8 |EFG1 |HCH1 |HSP90 |KEX2 |NOP1 |RAS1 |MORE
Yu SJ, et al. (2018) Deletion of ADA2 Increases Antifungal Drug Susceptibility and Virulence in Candida glabrata. Antimicrob Agents Chemother 62(3)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. glabrata |ADA2 |CAGL0G05269g |CAGL0L01771g |EPA20 |EPA23 |ERG6 |GAS3 |GCN5 |YPS10 |YPS4
Znaidi S, et al. (2018) Systematic gene overexpression in Candida albicans identifies a regulator of early adaptation to the mammalian gut. Cell Microbiol 20(11):e12890
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale phenotype analysisC. albicans |CRZ2
Azadmanesh J, et al. (2017) Filamentation Involves Two Overlapping, but Distinct, Programs of Filamentation in the Pathogenic Fungus Candida albicans. G3 (Bethesda) 7(11):3797-3808
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression study, Large-scale phenotype analysisC. albicans |C1_04630C_A |C4_00610W_A |C4_04090C_A |C6_02740W_A |COX4 |CR_03430W_A |GPA2 |IRE1 |KEX2 |KRE5 |PEP8 |PHR1 |RFG1 |RIM101 |MORE
Basso V, et al. (2017) The two-component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis-induced ROS accumulation. Mol Microbiol 106(1):157-182
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |CPH1 |EFG1 |SKN7 |UME6
Bernardo RT, et al. (2017) The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata. G3 (Bethesda) 7(1):1-18
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. glabrata |CAGL0E03740g |CAGL0G05632g |FPS1 |FPS2 |HAA1 |PMA1 |RSB1 |SSA3 |TPO3 |YPS4
Biswas C, et al. (2017) Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance. J Vis Exp (130)
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. glabrata |CDR1 |FCY2 |FKS1 |FKS2 |PDR1
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