Genome-wide Analysis papers

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Genome-wide AnalysisProteome-wide Analysis
Comparative genomic hybridizationLarge-scale protein detection
Computational analysisLarge-scale protein interaction
Genomic co-immunoprecipitation studyLarge-scale protein localization
Genomic expression studyLarge-scale protein modification
Large-scale genetic interactionOther large-scale proteomic analysis
Large-scale phenotype analysis 
Other genomic analysis 

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ReferenceLiterature TopicSpeciesGenes Addressed
Barber AE, et al. (2019) Comparative Genomics of Serial Candida glabrata Isolates and the Rapid Acquisition of Echinocandin Resistance during Therapy. Antimicrob Agents Chemother 63(2)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Other genomic analysisC. glabrata |FKS2 |FPR1 |MDE1
Bravo Ruiz G, et al. (2019) Rapid and extensive karyotype diversification in haploid clinical Candida auris isolates. Curr Genet 65(5):1217-1228
CGD Papers Entry  Pubmed Entry  
Other genomic analysis
Carrete L, et al. (2019) Genome Comparisons of Candida glabrata Serial Clinical Isolates Reveal Patterns of Genetic Variation in Infecting Clonal Populations. Front Microbiol 10:112
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Other genomic analysisC. albicans |CDR1 |CDR2 |ERG11 |ERG3 |ERG9 |FEN1 |GSL2 |QDR2 |SNQ2
C. glabrata |CAGL0B00242g |CAGL0F09273g |CAGL0J01774g |CAGL0J02530g |CAGL0L00227g |CAGL0M08756g |CDR1 |ERG11 |ERG3 |ERG9 |FEN1 |FKS1 |FKS2 |FLR1 |MORE
Castanheira M, et al. (2019) Analysis of Global Antifungal Surveillance Results Reveals Predominance of Erg11 Y132F Alteration among Azole-Resistant Candida parapsilosis and Candida tropicalis and Country-Specific Isolate Dissemination. Int J Antimicrob Agents
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. albicans |CDR1 |ERG11 |MDR1
C. glabrata |CDR1 |ERG11
C. dubliniensis |CDR1 |Cd36_84000 |ERG11 |MDR1
C. parapsilosis |CDR1 |ERG11 |MDR1
Chinnici J, et al. (2019) Candida albicans cell wall integrity transcription factors regulate polymicrobial biofilm formation with Streptococcus gordonii. PeerJ 7:e7870
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |ACE2 |ASH1 |BAS1 |BCR1 |BRG1 |CAS5 |CPH2 |CRZ1 |CSR1 |CTA4 |CUP9 |CWT1 |CZF1 |EFG1 |MORE
Cottier F, et al. (2019) Remasking of Candida albicans beta-Glucan in Response to Environmental pH Is Regulated by Quorum Sensing. MBio 10(5)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |CHT2 |EFG1
Das S, et al. (2019) Network analysis of hyphae forming proteins in Candida albicans identifies important proteins responsible for pathovirulence in the organism. Heliyon 5(6):e01916
CGD Papers Entry  Pubmed Entry  
Computational analysisC. albicans |ACT1 |BEM1 |CDC10 |CDC11 |CDC24 |CDC28 |CDC42 |CLA4 |CLN3 |CYR1 |HGC1 |HOG1 |HSP90 |PBS2 |MORE
Duvenage L, et al. (2019) Inhibition of Classical and Alternative Modes of Respiration in Candida albicans Leads to Cell Wall Remodeling and Increased Macrophage Recognition. MBio 10(1)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |AOX1 |AOX2 |FBP1 |GPM1 |GPM2 |ICL1 |MLS1 |PCK1 |PGI1 |PGK1 |UPC2 |YHB1
El Khoury P, et al. (2019) Phenotypic and Cell Wall Proteomic Characterization of a DDR48 mutant Candida albicans Strain. J Microbiol Biotechnol
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |ALS3 |CR_01020C_A |DDR48 |ECE1 |HSP90 |HYR4 |IPP1 |PGA4 |PMT1 |PRA1 |RIM9 |SOD4 |SOD6 |UTR2
Guo X, et al. (2019) Understand the genomic diversity and evolution of fungal pathogen Candida glabrata by genome-wide analysis of genetic variations. Methods
CGD Papers Entry  Pubmed Entry  
Computational analysisC. glabrata |CST6 |EPA10 |EPA9
Huang MY, et al. (2019) Circuit diversification in a biofilm regulatory network. PLoS Pathog 15(5):e1007787
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |BCR1 |BRG1 |EFG1 |UME6
Islam A, et al. (2019) Mms21: A Putative SUMO E3 Ligase in Candida albicans That Negatively Regulates Invasiveness and Filamentation, and Is Required for the Genotoxic and Cellular Stress Response. Genetics 211(2):579-595
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |ALS1 |ALS3 |BUB3 |DAP1 |ECE1 |EFG1 |HGC1 |HNT2 |HWP1 |MMS21 |PGA13 |PGA26 |RAD2 |SOD4 |MORE
Jakab A, et al. (2019) Physiological and Transcriptional Responses of Candida parapsilosis to Exogenous Tyrosol. Appl Environ Microbiol 85(20)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. parapsilosis |CDR1 |FAD2 |FAD3 |MDR1
C. albicans |CDR1 |FAD2 |FAD3 |MDR1
Karkowska-Kuleta J, et al. (2019) Moonlighting proteins are variably exposed at the cell surfaces of Candida glabrata, Candida parapsilosis and Candida tropicalis under certain growth conditions. BMC Microbiol 19(1):149
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |ENO1 |PDC11 |TDH3
C. glabrata |ADH1 |AHP1 |BAT2 |CAGL0H06633g |CAGL0K03289g |ENO1 |FBA1 |GND1 |GPM1 |IPP1 |PDC |PGI1 |PGK1 |PMU1 |MORE
C. parapsilosis |ADH1 |ALD5 |CPAR2_101620 |CPAR2_202600 |CPAR2_207210 |CPAR2_211810 |CPAR2_401230 |CPAR2_602950 |CPAR2_807980 |CPAR2_808670 |GND1 |ILV5 |PDC11 |PGI1
Konecna K, et al. (2019) A comparative analysis of protein virulence factors released via extracellular vesicles in two Candida albicans strains cultivated in a nutrient-limited medium. Microb Pathog 136:103666
CGD Papers Entry  Pubmed Entry  
Large-scale protein localizationC. albicans |ALS2 |ALS3 |ALS4 |ASC1 |ATC1 |BGL2 |BMH1 |CRH11 |ECM33 |ENO1 |FET34 |HEX1 |HSP90 |MP65 |MORE
Lee SY, et al. (2019) The Transcription Factor Sfp1 Regulates the Oxidative Stress Response in Candida albicans. Microorganisms 7(5)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |CAP1 |HOG1 |SFP1
Liao Z, et al. (2019) Metabonomics on Candida albicans indicate the excessive H3K56ac is involved in the antifungal activity of Shikonin. Emerg Microbes Infect 8(1):1243-1253
CGD Papers Entry  Pubmed Entry  
Other large-scale proteomic analysisC. albicans |HST3
Lombardi L, et al. (2019) Characterization of the Candida orthopsilosis agglutinin-like sequence (ALS) genes. PLoS One 14(4):e0215912
CGD Papers Entry  Pubmed Entry  
Computational analysis
McCarthy CGP and Fitzpatrick DA (2019) Pan-genome analyses of model fungal species. Microb Genom 5(2)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Other genomic analysis
O'Meara TR, et al. (2019) Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen. PLoS Biol 17(7):e3000358
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale protein interactionC. albicans |AHA1 |C3_00950C_A |CDC37 |CNS1 |CPR6 |HCH1 |HSP90 |RVB1 |RVB2 |SBA1 |SGT1 |STI1
Pais P, et al. (2019) Draft Genome Sequences of Three Clinical Isolates of the Pathogenic Yeast Candida glabrata. Microbiol Resour Announc 8(35)
CGD Papers Entry  Pubmed Entry  
Other genomic analysis
Romo JA, et al. (2019) Global Transcriptomic Analysis of the Candida albicans Response to Treatment with a Novel Inhibitor of Filamentation. mSphere 4(5)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |ALS3 |ECE1 |SAP5
Schoeters F and Van Dijck P (2019) Protein-Protein Interactions in Candida albicans. Front Microbiol 10:1792
CGD Papers Entry  Pubmed Entry  
Large-scale protein interaction
Sellam A, et al. (2019) The p38/HOG stress-activated protein kinase network couples growth to division in Candida albicans. PLoS Genet 15(3):e1008052
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale phenotype analysisC. albicans |ACE2 |AHR1 |ARO80 |ASG1 |ASH1 |BAS1 |BCR1 |C2_01870C_A |C2_05640W_A |C2_06600W_A |C2_08860W_A |C2_10540W_A |C2_10700C_A |C4_05870C_A |MORE
Shivarathri R, et al. (2019) The Fungal Histone Acetyl Transferase Gcn5 Controls Virulence of the Human Pathogen Candida albicans through Multiple Pathways. Sci Rep 9(1):9445
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |CEK1 |EFG1 |GCN5 |GSC1 |GSL1 |HOG1 |MKC1
Spettel K, et al. (2019) Analysis of antifungal resistance genes in Candida albicans and Candida glabrata using next generation sequencing. PLoS One 14(1):e0210397
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale phenotype analysisC. albicans |CDR1 |ERG11 |ERG3 |GSC1 |GSL1 |GSL2 |TAC1
C. glabrata |CDR1 |ERG11 |ERG3 |FKS1 |FKS2
Wang FJ and Liu ZH (2019) Systematic analysis of protein expression in Candida albicans exposed to farnesol. Chin Med J (Engl) 132(19):2348-2353
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |ERG1 |ERG24 |ERG25 |ERG26 |ERG27 |ERG3 |ERG4 |ERG5 |ERG6
Yeh SJ, et al. (2019) Investigating Common Pathogenic Mechanisms between Homo sapiens and Different Strains of Candida albicans for Drug Design: Systems Biology Approach via Two-Sided NGS Data Identification. Toxins (Basel) 11(2)
CGD Papers Entry  Pubmed Entry  
Computational analysisC. albicans |FLO8 |HHF22 |NAM7 |SAP5 |SAP6 |SAS2 |SUV3 |YBP1
Allert S, et al. (2018) Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers. MBio 9(3)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale phenotype analysisC. albicans |AAF1 |ALS3 |BAS1 |C1_01490W_A |C1_07480C_A |CPH1 |DEF1 |ECE1 |HGC1 |HMA1 |KEX1 |NPR2 |PEP12 |SAP1 |MORE
Awad A, et al. (2018) Proteomic analysis of a Candida albicans pga1 Null Strain. EuPA Open Proteom 18:1-6
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |APE2 |CDC11 |CDR1 |CDR2 |CFL1 |CR_03530W_A |EGD2 |ERG1 |ERG11 |EXG2 |HSP70 |HSP90 |INT1 |LIP10 |MORE
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