Genome-wide Analysis papers

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Genome-wide AnalysisProteome-wide Analysis
Comparative genomic hybridizationLarge-scale protein detection
Computational analysisLarge-scale protein interaction
Genomic co-immunoprecipitation studyLarge-scale protein localization
Genomic expression studyLarge-scale protein modification
Large-scale genetic interactionOther large-scale proteomic analysis
Large-scale phenotype analysis 
Other genomic analysis 

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ReferenceLiterature TopicSpeciesGenes Addressed
Allert S, et al. (2018) Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers. MBio 9(3)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale phenotype analysisC. albicans |AAF1 |ALS3 |BAS1 |C1_01490W_A |C1_07480C_A |CPH1 |DEF1 |ECE1 |HGC1 |HMA1 |KEX1 |NPR2 |PEP12 |SAP1 |MORE
Awad A, et al. (2018) Proteomic analysis of a Candida albicans pga1 Null Strain. EuPA Open Proteom 18:1-6
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |APE2 |CDC11 |CDR1 |CDR2 |CFL1 |CR_03530W_A |EGD2 |ERG1 |ERG11 |EXG2 |HSP70 |HSP90 |INT1 |LIP10 |MORE
Awad A, et al. (2018) Tandem Mass Spectrometric Cell Wall Proteome Profiling of a Candida albicans hwp2 Mutant Strain. Curr Mol Pharmacol
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |CHT2 |HWP2 |MTS1 |PGA28 |PGA32 |PGA41 |PGA50 |PHR1 |RBR1 |SAP10 |SAP4 |SAP5
Caplan T, et al. (2018) Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans. Cell Rep 23(8):2292-2298
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Large-scale phenotype analysisC. albicans |AHR1 |BCK1 |C6_00530C_A |CAS5 |CAT1 |CCT8 |DBP8 |GSC1 |GSL1 |HSP90 |KEX2 |MKC1 |NOP14 |PKC1 |MORE
El Khoury P, et al. (2018) Proteomic analysis of a Candida albicans pir32 null strain reveals proteins involved in adhesion, filamentation and virulence. PLoS One 13(3):e0194403
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale protein detectionC. albicans |ALS3 |CDC42 |CSA2 |DCW1 |DFG5 |PIR32 |RBT5 |SSR1 |SSU81 |UCF1 |XOG1
Forche A, et al. (2018) Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans. Genetics 209(3):725-741
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. albicans |GAL1
Herrero-de-Dios C, et al. (2018) Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs. MBio 9(2)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |HOG1
Kaneva IN, et al. (2018) Quantitative Proteomic Analysis in Candida albicans Using SILAC-Based Mass Spectrometry. Proteomics 18(5-6):e1700278
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |ARG4 |CDC14
Mount HO, et al. (2018) Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. PLoS Genet 14(4):e1007319
CGD Papers Entry  Pubmed Entry  
Large-scale genetic interaction, Large-scale phenotype analysisC. albicans |APM1 |CR_03430W_A |ERG3 |ERG5 |GZF3 |KIC1 |MRR2 |NPR2 |PBS2 |PEP8 |RCY1 |RGD1 |SET6 |SSK2 |MORE
Thakre A, et al. (2018) Limonene inhibits Candida albicans growth by inducing apoptosis. Med Mycol 56(5):565-578
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |C6_02480W_A |CCT8 |CRN1 |CR_04650W_A |EBP1 |KRE6 |MBF1 |NPL3 |PIL1 |PIN3 |RHR2 |RPL11 |RPL15A |RPL29 |MORE
Tripathi H and Khan F (2018) Identification of potential inhibitors against nuclear Dam1 complex subunit Ask1 of Candida albicans using virtual screening and MD simulations. Comput Biol Chem 72:33-44
CGD Papers Entry  Pubmed Entry  
Computational analysisC. albicans |ASK1 |DAM1
Tucey TM, et al. (2018) Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection. Cell Metab 27(5):988-1006.e7
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |GAL4 |TYE7
Turner SA, et al. (2018) Dal81 Regulates Expression of Arginine Metabolism Genes in Candida parapsilosis. mSphere 3(2)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. parapsilosis |DAL81 |GAT1 |GCN4 |GZF3 |PUT3 |UGA3
Veri AO, et al. (2018) Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space. PLoS Genet 14(3):e1007270
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |ACT1 |AHA1 |BRG1 |BUB2 |C5_05270C_A |CDC37 |CPR6 |CTA8 |EFG1 |HCH1 |HSP90 |KEX2 |NOP1 |RAS1 |MORE
Yu SJ, et al. (2018) Deletion of ADA2 Increases Antifungal Drug Susceptibility and Virulence in Candida glabrata. Antimicrob Agents Chemother 62(3)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. glabrata |ADA2 |CAGL0G05269g |CAGL0L01771g |EPA20 |EPA23 |ERG6 |GAS3 |GCN5 |YPS10 |YPS4
Azadmanesh J, et al. (2017) Filamentation Involves Two Overlapping, but Distinct, Programs of Filamentation in the Pathogenic Fungus Candida albicans. G3 (Bethesda) 7(11):3797-3808
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Genomic expression study, Large-scale phenotype analysisC. albicans |C1_04630C_A |C4_00610W_A |C4_04090C_A |C6_02740W_A |COX4 |CR_03430W_A |GPA2 |IRE1 |KEX2 |KRE5 |PEP8 |PHR1 |RFG1 |RIM101 |MORE
Basso V, et al. (2017) The two-component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis-induced ROS accumulation. Mol Microbiol 106(1):157-182
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Genomic expression studyC. albicans |CPH1 |EFG1 |SKN7 |UME6
Bernardo RT, et al. (2017) The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata. G3 (Bethesda) 7(1):1-18
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. glabrata |CAGL0E03740g |CAGL0G05632g |FPS1 |FPS2 |HAA1 |PMA1 |RSB1 |SSA3 |TPO3 |YPS4
Biswas C, et al. (2017) Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance. J Vis Exp (130)
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. glabrata |CDR1 |FCY2 |FKS1 |FKS2 |PDR1
Cao C, et al. (2017) Global regulatory roles of the cAMP/PKA pathway revealed by phenotypic, transcriptomic and phosphoproteomic analyses in a null mutant of the PKA catalytic subunit in Candida albicans. Mol Microbiol 105(1):46-64
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |AGP2 |ALS3 |ALS4 |AOX2 |BRG1 |CAN1 |CAT1 |CCP1 |CPH1 |CSA2 |CYR1 |DIP5 |ECE1 |ERG13 |MORE
Chaillot J, et al. (2017) Genome-Wide Screen for Haploinsufficient Cell Size Genes in the Opportunistic Yeast Candida albicans. G3 (Bethesda) 7(2):355-360
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Large-scale phenotype analysisC. albicans |ABD1 |ADE6 |AFT2 |AGM1 |AHR1 |ALI1 |ALK6 |ALK8 |ALO1 |ALT1 |APS3 |ARC19 |ARF3 |ARO3 |MORE
Chebaro Y, et al. (2017) Adaptation of Candida albicans to Reactive Sulfur Species. Genetics 206(1):151-162
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |CTA4 |ECM17 |MET16 |SSU1 |ZCF2
Cottier F, et al. (2017) The Transcriptional Response of Candida albicans to Weak Organic Acids, Carbon Source, and MIG1 Inactivation Unveils a Role for HGT16 in Mediating the Fungistatic Effect of Acetic Acid. G3 (Bethesda) 7(11):3597-3604
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |HGT16 |MIG1
Dorsaz S, et al. (2017) Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens. Antimicrob Agents Chemother 61(9)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |ERG4 |ERG6
Flanagan PR, et al. (2017) The Candida albicans TOR-Activating GTPases Gtr1 and Rhb1 Coregulate Starvation Responses and Biofilm Formation. mSphere 2(6)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |GTR1 |MEP2 |RHB1 |SKO1 |TOR1
Garcia C, et al. (2017) The Human Gut Microbial Metabolome Modulates Fungal Growth via the TOR Signaling Pathway. mSphere 2(6)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |TOR1
Leach MD, et al. (2017) Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity. G3 (Bethesda) 7(1):95-108
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Other large-scale proteomic analysisC. albicans |SGT2 |SIS1
Li DD, et al. (2017) Potent In Vitro Synergism of Fluconazole and Osthole against Fluconazole-Resistant Candida albicans. Antimicrob Agents Chemother 61(8)
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |CAS5 |CAT1 |ECM17 |HGT6 |MAS2 |MDR1 |NAG3 |OGG1 |PDX3 |PTR2
Markus B, et al. (2017) Proteomic analysis of protein phosphatase Z1 from Candida albicans. PLoS One 12(8):e0183176
CGD Papers Entry  Pubmed Entry  
Large-scale protein modificationC. albicans |EFT2 |PPZ1 |RPP0
Nocedal I, et al. (2017) Gene regulatory network plasticity predates a switch in function of a conserved transcription regulator. Elife 6
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |NDT80
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