| Reference | Literature Topic | Species | Genes Addressed |
|---|
Allert S, et al. (2018) Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers. MBio 9(3)
    | Large-scale phenotype analysis | C. albicans | |AAF1 |ALS3 |BAS1 |C1_01490W_A |C1_07480C_A |CPH1 |DEF1 |ECE1 |HGC1 |HMA1 |KEX1 |NPR2 |PEP12 |SAP1 |MORE |
Awad A, et al. (2018) Proteomic analysis of a Candida albicans pga1 Null Strain. EuPA Open Proteom 18:1-6
| Large-scale protein detection | C. albicans | |APE2 |CDC11 |CDR1 |CDR2 |CFL1 |CR_03530W_A |EGD2 |ERG1 |ERG11 |EXG2 |HSP70 |HSP90 |INT1 |LIP10 |MORE |
Awad A, et al. (2018) Tandem Mass Spectrometric Cell Wall Proteome Profiling of a Candida albicans hwp2 Mutant Strain. Curr Mol Pharmacol
| Large-scale protein detection | C. albicans | |CHT2 |HWP2 |MTS1 |PGA28 |PGA32 |PGA41 |PGA50 |PHR1 |RBR1 |SAP10 |SAP4 |SAP5 |
Caplan T, et al. (2018) Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans. Cell Rep 23(8):2292-2298
| Large-scale phenotype analysis | C. albicans | |AHR1 |BCK1 |C6_00530C_A |CAS5 |CAT1 |CCT8 |DBP8 |GSC1 |GSL1 |HSP90 |KEX2 |MKC1 |NOP14 |PKC1 |MORE |
El Khoury P, et al. (2018) Proteomic analysis of a Candida albicans pir32 null strain reveals proteins involved in adhesion, filamentation and virulence. PLoS One 13(3):e0194403
| Large-scale protein detection | C. albicans | |ALS3 |CDC42 |CSA2 |DCW1 |DFG5 |PIR32 |RBT5 |SSR1 |SSU81 |UCF1 |XOG1 |
Forche A, et al. (2018) Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans. Genetics 209(3):725-741
| Other genomic analysis | C. albicans | |GAL1 |
Herrero-de-Dios C, et al. (2018) Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs. MBio 9(2)
| Genomic expression study | C. albicans | |HOG1 |
Kaneva IN, et al. (2018) Quantitative Proteomic Analysis in Candida albicans Using SILAC-Based Mass Spectrometry. Proteomics 18(5-6):e1700278
| Large-scale protein detection | C. albicans | |ARG4 |CDC14 |
Mount HO, et al. (2018) Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. PLoS Genet 14(4):e1007319
| Large-scale genetic interaction, Large-scale phenotype analysis | C. albicans | |APM1 |CR_03430W_A |ERG3 |ERG5 |GZF3 |KIC1 |MRR2 |NPR2 |PBS2 |PEP8 |RCY1 |RGD1 |SET6 |SSK2 |MORE |
Thakre A, et al. (2018) Limonene inhibits Candida albicans growth by inducing apoptosis. Med Mycol 56(5):565-578
| Large-scale protein detection | C. albicans | |C6_02480W_A |CCT8 |CRN1 |CR_04650W_A |EBP1 |KRE6 |MBF1 |NPL3 |PIL1 |PIN3 |RHR2 |RPL11 |RPL15A |RPL29 |MORE |
Tripathi H and Khan F (2018) Identification of potential inhibitors against nuclear Dam1 complex subunit Ask1 of Candida albicans using virtual screening and MD simulations. Comput Biol Chem 72:33-44
| Computational analysis | C. albicans | |ASK1 |DAM1 |
Tucey TM, et al. (2018) Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection. Cell Metab 27(5):988-1006.e7
| Genomic expression study | C. albicans | |GAL4 |TYE7 |
Turner SA, et al. (2018) Dal81 Regulates Expression of Arginine Metabolism Genes in Candida parapsilosis. mSphere 3(2)
| Genomic expression study | C. parapsilosis | |DAL81 |GAT1 |GCN4 |GZF3 |PUT3 |UGA3 |
Veri AO, et al. (2018) Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space. PLoS Genet 14(3):e1007270
| Genomic expression study | C. albicans | |ACT1 |AHA1 |BRG1 |BUB2 |C5_05270C_A |CDC37 |CPR6 |CTA8 |EFG1 |HCH1 |HSP90 |KEX2 |NOP1 |RAS1 |MORE |
Yu SJ, et al. (2018) Deletion of ADA2 Increases Antifungal Drug Susceptibility and Virulence in Candida glabrata. Antimicrob Agents Chemother 62(3)
| Genomic expression study | C. glabrata | |ADA2 |CAGL0G05269g |CAGL0L01771g |EPA20 |EPA23 |ERG6 |GAS3 |GCN5 |YPS10 |YPS4 |
Azadmanesh J, et al. (2017) Filamentation Involves Two Overlapping, but Distinct, Programs of Filamentation in the Pathogenic Fungus Candida albicans. G3 (Bethesda) 7(11):3797-3808
| Genomic expression study, Large-scale phenotype analysis | C. albicans | |C1_04630C_A |C4_00610W_A |C4_04090C_A |C6_02740W_A |COX4 |CR_03430W_A |GPA2 |IRE1 |KEX2 |KRE5 |PEP8 |PHR1 |RFG1 |RIM101 |MORE |
Basso V, et al. (2017) The two-component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis-induced ROS accumulation. Mol Microbiol 106(1):157-182
| Genomic expression study | C. albicans | |CPH1 |EFG1 |SKN7 |UME6 |
Bernardo RT, et al. (2017) The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata. G3 (Bethesda) 7(1):1-18
| Genomic expression study | C. glabrata | |CAGL0E03740g |CAGL0G05632g |FPS1 |FPS2 |HAA1 |PMA1 |RSB1 |SSA3 |TPO3 |YPS4 |
Biswas C, et al. (2017) Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance. J Vis Exp (130)
| Other genomic analysis | C. glabrata | |CDR1 |FCY2 |FKS1 |FKS2 |PDR1 |
Cao C, et al. (2017) Global regulatory roles of the cAMP/PKA pathway revealed by phenotypic, transcriptomic and phosphoproteomic analyses in a null mutant of the PKA catalytic subunit in Candida albicans. Mol Microbiol 105(1):46-64
| Genomic expression study | C. albicans | |AGP2 |ALS3 |ALS4 |AOX2 |BRG1 |CAN1 |CAT1 |CCP1 |CPH1 |CSA2 |CYR1 |DIP5 |ECE1 |ERG13 |MORE |
Chaillot J, et al. (2017) Genome-Wide Screen for Haploinsufficient Cell Size Genes in the Opportunistic Yeast Candida albicans. G3 (Bethesda) 7(2):355-360
| Large-scale phenotype analysis | C. albicans | |ABD1 |ADE6 |AFT2 |AGM1 |AHR1 |ALI1 |ALK6 |ALK8 |ALO1 |ALT1 |APS3 |ARC19 |ARF3 |ARO3 |MORE |
Chebaro Y, et al. (2017) Adaptation of Candida albicans to Reactive Sulfur Species. Genetics 206(1):151-162
| Genomic expression study | C. albicans | |CTA4 |ECM17 |MET16 |SSU1 |ZCF2 |
Cottier F, et al. (2017) The Transcriptional Response of Candida albicans to Weak Organic Acids, Carbon Source, and MIG1 Inactivation Unveils a Role for HGT16 in Mediating the Fungistatic Effect of Acetic Acid. G3 (Bethesda) 7(11):3597-3604
| Genomic expression study | C. albicans | |HGT16 |MIG1 |
Dorsaz S, et al. (2017) Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens. Antimicrob Agents Chemother 61(9)
| Genomic expression study | C. albicans | |ERG4 |ERG6 |
Flanagan PR, et al. (2017) The Candida albicans TOR-Activating GTPases Gtr1 and Rhb1 Coregulate Starvation Responses and Biofilm Formation. mSphere 2(6)
| Genomic expression study | C. albicans | |GTR1 |MEP2 |RHB1 |SKO1 |TOR1 |
Garcia C, et al. (2017) The Human Gut Microbial Metabolome Modulates Fungal Growth via the TOR Signaling Pathway. mSphere 2(6)
| Genomic expression study | C. albicans | |TOR1 |
Leach MD, et al. (2017) Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity. G3 (Bethesda) 7(1):95-108
| Other large-scale proteomic analysis | C. albicans | |SGT2 |SIS1 |
Li DD, et al. (2017) Potent In Vitro Synergism of Fluconazole and Osthole against Fluconazole-Resistant Candida albicans. Antimicrob Agents Chemother 61(8)
| Genomic expression study | C. albicans | |CAS5 |CAT1 |ECM17 |HGT6 |MAS2 |MDR1 |NAG3 |OGG1 |PDX3 |PTR2 |
Markus B, et al. (2017) Proteomic analysis of protein phosphatase Z1 from Candida albicans. PLoS One 12(8):e0183176
| Large-scale protein modification | C. albicans | |EFT2 |PPZ1 |RPP0 |
Nocedal I, et al. (2017) Gene regulatory network plasticity predates a switch in function of a conserved transcription regulator. Elife 6
| Genomic expression study | C. albicans | |NDT80 |
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