| Reference | Literature Topic | Species | Genes Addressed |
|---|
Alkafeef SS, et al. (2020) Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes. PLoS Genet 16(6):e1008881
    | Large-scale protein interaction | C. albicans | |C1_07630W_A |GRX3 |HAP43 |SFU1 |
Alves R, et al. (2020) Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source. NPJ Biofilms Microbiomes 6:4
| Genomic expression study | C. glabrata | |CAGL0F08239g |CAGL0J07980g |CAGL0K10274g |ERG11 |ERG9 |FTR1 |MGE1 |
Caplan T, et al. (2020) Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2. Cell Chem Biol
| Large-scale phenotype analysis | C. albicans | |ALS3 |CHS1 |CHS2 |CHS3 |CHS8 |DDR48 |HRR25 |SOD5 |STP4 |URK1 |YCK2 |
Dawson CS, et al. (2020) Protein markers for Candida albicans EVs include claudin-like Sur7 family proteins. J Extracell Vesicles 9(1):1750810
| Large-scale protein localization | C. albicans | |ARF3 |BGL2 |BRO1 |C1_04200C_A |C2_08160C_A |C4_04800W_A |CAN1 |CAN2 |CDC42 |CDR1 |CDR2 |CHS3 |CRH11 |ECM33 |MORE |
Ev LD, et al. (2020) The role of Candida albicans in root caries biofilms: an RNA-seq analysis. J Appl Oral Sci 28:e20190578
| Genomic expression study | C. albicans | |ASR1 |C3_01020W_A |C7_03850W_A |GUT1 |HGT19 |ITR1 |STT4 |UTP20 |
Feng J, et al. (2020) Hof1 plays a checkpoint related role in MMS induced DNA damage response in Candida albicans. Mol Biol Cell :mbcE19060316
| Large-scale phenotype analysis | C. albicans | |HOF1 |NOC2 |RAD23 |RAD4 |RAD53 |
Goncalves B, et al. (2020) Effect of progesterone on Candida albicans biofilm formation under acidic conditions: A transcriptomic analysis. Int J Med Microbiol :151414
| Genomic expression study | C. albicans | |ADH2 |AGP3 |AHR1 |ALS1 |ALS5 |ATO1 |ATP6 |ATP9 |BRG1 |C1_00160C_A |C1_01130W_A |C1_01630W_A |C1_07160C_A |C1_13130C_A |MORE |
Gong J, et al. (2020) The Als3 cell wall adhesin plays a critical role in human Serum amyloid A1 (SAA1)-induced cell death and aggregation in Candida albicans. Antimicrob Agents Chemother
| Genomic expression study | C. albicans | |AHR1 |ALS3 |BCR1 |EFG1 |
Khemiri I, et al. (2020) Transcriptome Analysis Uncovers a Link Between Copper Metabolism, and Both Fungal Fitness and Antifungal Sensitivity in the Opportunistic Yeast Candida albicans. Front Microbiol 11:935
| Genomic expression study | C. albicans | |ATX1 |CRP1 |CTR1 |CUP1 |FRE7 |MAC1 |
Lagree K, et al. (2020) Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. PLoS Genet 16(1):e1008582
| Genomic expression study | C. albicans | |CDC19 |CTN1 |ENO1 |FOX2 |GAL1 |GPM1 |HGT1 |HXK2 |ICL1 |MIG1 |MIG2 |MLS1 |PFK1 |PFK2 |MORE |
Miramon P, et al. (2020) The paralogous transcription factors Stp1 and Stp2 of Candida albicans have distinct functions in nutrient acquisition and host interaction. Infect Immun
| Genomic expression study | C. albicans | |PTR3 |SFL2 |SSY1 |SSY5 |STP1 |STP2 |UME6 |
Rasheed M, et al. (2020) Global Secretome Characterization of the Pathogenic Yeast Candida glabrata. J Proteome Res 19(1):49-63
| Large-scale protein localization | C. glabrata | |ACT1 |ADH1 |AHP1 |CAGL0A00979g |CAGL0A01474g |CAGL0A01540g |CAGL0A01870g |CAGL0A03117g |CAGL0A03278g |CAGL0B01100g |CAGL0C02453g |CAGL0C02475g |CAGL0C04389g |CAGL0C04411g |MORE |
Sitterle E, et al. (2020) Large-scale genome mining allows identification of neutral polymorphisms and novel resistance mutations in genes involved in Candida albicans resistance to azoles and echinocandins. J Antimicrob Chemother
| Other genomic analysis | C. albicans | |ERG11 |GSC1 |GSL1 |MRR1 |TAC1 |UPC2 |
Thomas G, et al. (2020) Identifying Candida albicans Gene Networks Involved in Pathogenicity. Front Genet 11:375
| Computational analysis, Genomic expression study | C. albicans | |AHR1 |CST20 |GRR1 |HGC1 |HIT1 |HOG1 |HST7 |HWP1 |INT1 |PBS2 |PEP8 |RIM101 |RSR1 |SEF1 |MORE |
Truong T, et al. (2020) Proteomics Analysis of Candida albicans dnm1 Haploid Mutant Unraveled the Association Between Mitochondrial Fission and Antifungal Susceptibility. Proteomics :e1900240
| Large-scale protein detection, Genomic expression study | C. albicans | |DNM1 |
Verma R, et al. (2020) Genome-wide screening and in silico gene knockout to predict potential candidates for drug designing against Candida albicans. Infect Genet Evol :104196
| Computational analysis | C. albicans | |ERG5 |FAS2 |FOL1 |
Wallace EWJ, et al. (2020) Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom. Nucleic Acids Res 48(5):2312-2331
| Computational analysis |
Xu H, et al. (2020) RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans. Cell Commun Signal 18(1):1
| Genomic expression study | C. albicans | |CRZ1 |
Yang D, et al. (2020) Candida albicans Ubiquitin and Heat Shock Factor-Type Transcriptional Factors Are Involved in 2-Dodecenoic Acid-Mediated Inhibition of Hyphal Growth. Microorganisms 8(1)
| Genomic expression study | C. albicans | |SFL1 |SFL2 |UBI4 |
Barber AE, et al. (2019) Comparative Genomics of Serial Candida glabrata Isolates and the Rapid Acquisition of Echinocandin Resistance during Therapy. Antimicrob Agents Chemother 63(2)
| Other genomic analysis | C. glabrata | |FKS2 |FPR1 |MDE1 |
Bravo Ruiz G, et al. (2019) Rapid and extensive karyotype diversification in haploid clinical Candida auris isolates. Curr Genet 65(5):1217-1228
| Other genomic analysis |
Carrete L, et al. (2019) Genome Comparisons of Candida glabrata Serial Clinical Isolates Reveal Patterns of Genetic Variation in Infecting Clonal Populations. Front Microbiol 10:112
| Other genomic analysis | C. albicans | |CDR1 |CDR2 |ERG11 |ERG3 |ERG9 |FEN1 |GSL2 |QDR2 |SNQ2 |
| | C. glabrata | |CAGL0B00242g |CAGL0F09273g |CAGL0J01774g |CAGL0J02530g |CAGL0L00227g |CAGL0M08756g |CDR1 |ERG11 |ERG3 |ERG9 |FEN1 |FKS1 |FKS2 |FLR1 |MORE |
Castanheira M, et al. (2019) Analysis of Global Antifungal Surveillance Results Reveals Predominance of Erg11 Y132F Alteration among Azole-Resistant Candida parapsilosis and Candida tropicalis and Country-Specific Isolate Dissemination. Int J Antimicrob Agents
| Other genomic analysis | C. albicans | |CDR1 |ERG11 |MDR1 |
| | C. glabrata | |CDR1 |ERG11 |
| | C. parapsilosis | |CDR1 |ERG11 |MDR1 |
| | C. dubliniensis | |CDR1 |Cd36_84000 |ERG11 |MDR1 |
Chinnici J, et al. (2019) Candida albicans cell wall integrity transcription factors regulate polymicrobial biofilm formation with Streptococcus gordonii. PeerJ 7:e7870
| Large-scale protein detection | C. albicans | |ACE2 |ASH1 |BAS1 |BCR1 |BRG1 |CAS5 |CPH2 |CRZ1 |CSR1 |CTA4 |CUP9 |CWT1 |CZF1 |EFG1 |MORE |
Cottier F, et al. (2019) Remasking of Candida albicans beta-Glucan in Response to Environmental pH Is Regulated by Quorum Sensing. MBio 10(5)
| Genomic expression study | C. albicans | |CHT2 |EFG1 |
Das S, et al. (2019) Network analysis of hyphae forming proteins in Candida albicans identifies important proteins responsible for pathovirulence in the organism. Heliyon 5(6):e01916
| Computational analysis | C. albicans | |ACT1 |BEM1 |CDC10 |CDC11 |CDC24 |CDC28 |CDC42 |CLA4 |CLN3 |CYR1 |HGC1 |HOG1 |HSP90 |PBS2 |MORE |
Duvenage L, et al. (2019) Inhibition of Classical and Alternative Modes of Respiration in Candida albicans Leads to Cell Wall Remodeling and Increased Macrophage Recognition. MBio 10(1)
| Genomic expression study | C. albicans | |AOX1 |AOX2 |FBP1 |GPM1 |GPM2 |ICL1 |MLS1 |PCK1 |PGI1 |PGK1 |UPC2 |YHB1 |
El Khoury P, et al. (2019) Phenotypic and Cell Wall Proteomic Characterization of a DDR48 mutant Candida albicans Strain. J Microbiol Biotechnol
| Large-scale protein detection | C. albicans | |ALS3 |CR_01020C_A |DDR48 |ECE1 |HSP90 |HYR4 |IPP1 |PGA4 |PMT1 |PRA1 |RIM9 |SOD4 |SOD6 |UTR2 |
Guo X, et al. (2019) Understand the genomic diversity and evolution of fungal pathogen Candida glabrata by genome-wide analysis of genetic variations. Methods
| Computational analysis | C. glabrata | |CST6 |EPA10 |EPA9 |
Han TL, et al. (2019) A metabolomic study of the effect of Candida albicans glutamate dehydrogenase deletion on growth and morphogenesis. NPJ Biofilms Microbiomes 5(1):13
| Other large-scale proteomic analysis | C. albicans | |GDH2 |GDH3 |
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