| Reference | Literature Topic | Species | Genes Addressed |
|---|
Barber AE, et al. (2019) Comparative Genomics of Serial Candida glabrata Isolates and the Rapid Acquisition of Echinocandin Resistance during Therapy. Antimicrob Agents Chemother 63(2)
  | Other genomic analysis | C. glabrata | |FKS2 |FPR1 |MDE1 |
Carrete L, et al. (2019) Genome Comparisons of Candida glabrata Serial Clinical Isolates Reveal Patterns of Genetic Variation in Infecting Clonal Populations. Front Microbiol 10:112
  | Other genomic analysis | C. albicans | |CDR1 |CDR2 |ERG11 |ERG3 |ERG9 |FEN1 |GSL2 |QDR2 |SNQ2 |
| | C. glabrata | |CAGL0B00242g |CAGL0F09273g |CAGL0J01774g |CAGL0J02530g |CAGL0L00227g |CAGL0M08756g |CDR1 |ERG11 |ERG3 |ERG9 |FEN1 |FKS1 |FKS2 |FLR1 |MORE |
Duvenage L, et al. (2019) Inhibition of Classical and Alternative Modes of Respiration in Candida albicans Leads to Cell Wall Remodeling and Increased Macrophage Recognition. MBio 10(1)
| Genomic expression study | C. albicans | |AOX1 |AOX2 |FBP1 |GPM1 |GPM2 |ICL1 |MLS1 |PCK1 |PGI1 |PGK1 |UPC2 |YHB1 |
Islam A, et al. (2019) Mms21: A Putative SUMO E3 Ligase in Candida albicans That Negatively Regulates Invasiveness and Filamentation, and Is Required for the Genotoxic and Cellular Stress Response. Genetics 211(2):579-595
| Genomic expression study | C. albicans | |ALS1 |ALS3 |BUB3 |DAP1 |ECE1 |EFG1 |HGC1 |HNT2 |HWP1 |MMS21 |PGA13 |PGA26 |RAD2 |SOD4 |MORE |
McCarthy CGP and Fitzpatrick DA (2019) Pan-genome analyses of model fungal species. Microb Genom 5(2)
| Other genomic analysis |
Sellam A, et al. (2019) The p38/HOG stress-activated protein kinase network couples growth to division in Candida albicans. PLoS Genet 15(3):e1008052
| Large-scale phenotype analysis | C. albicans | |ACE2 |AHR1 |ARO80 |ASG1 |ASH1 |BAS1 |BCR1 |C2_01870C_A |C2_05640W_A |C2_06600W_A |C2_08860W_A |C2_10540W_A |C2_10700C_A |C4_05870C_A |MORE |
Spettel K, et al. (2019) Analysis of antifungal resistance genes in Candida albicans and Candida glabrata using next generation sequencing. PLoS One 14(1):e0210397
| Large-scale phenotype analysis | C. albicans | |CDR1 |ERG11 |ERG3 |GSC1 |GSL1 |GSL2 |TAC1 |
| | C. glabrata | |CDR1 |ERG11 |ERG3 |FKS1 |FKS2 |
Yeh SJ, et al. (2019) Investigating Common Pathogenic Mechanisms between Homo sapiens and Different Strains of Candida albicans for Drug Design: Systems Biology Approach via Two-Sided NGS Data Identification. Toxins (Basel) 11(2)
| Computational analysis | C. albicans | |FLO8 |HHF22 |NAM7 |SAP5 |SAP6 |SAS2 |SUV3 |YBP1 |
Allert S, et al. (2018) Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers. MBio 9(3)
| Large-scale phenotype analysis | C. albicans | |AAF1 |ALS3 |BAS1 |C1_01490W_A |C1_07480C_A |CPH1 |DEF1 |ECE1 |HGC1 |HMA1 |KEX1 |NPR2 |PEP12 |SAP1 |MORE |
Awad A, et al. (2018) Proteomic analysis of a Candida albicans pga1 Null Strain. EuPA Open Proteom 18:1-6
| Large-scale protein detection | C. albicans | |APE2 |CDC11 |CDR1 |CDR2 |CFL1 |CR_03530W_A |EGD2 |ERG1 |ERG11 |EXG2 |HSP70 |HSP90 |INT1 |LIP10 |MORE |
Awad A, et al. (2018) Tandem Mass Spectrometric Cell Wall Proteome Profiling of a Candida albicans hwp2 Mutant Strain. Curr Mol Pharmacol 11(3):211-225
| Large-scale protein detection | C. albicans | |CHT2 |HWP2 |MTS1 |PGA28 |PGA32 |PGA41 |PGA50 |PHR1 |RBR1 |SAP10 |SAP4 |SAP5 |
Biswas C, et al. (2018) Whole Genome Sequencing of Australian Candida glabrata Isolates Reveals Genetic Diversity and Novel Sequence Types. Front Microbiol 9:2946
| Other genomic analysis | C. glabrata | |FKS1 |FKS2 |MSH2 |PDR1 |
Caplan T, et al. (2018) Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans. Cell Rep 23(8):2292-2298
| Large-scale phenotype analysis | C. albicans | |AHR1 |BCK1 |C6_00530C_A |CAS5 |CAT1 |CCT8 |DBP8 |GSC1 |GSL1 |HSP90 |KEX2 |MKC1 |NOP14 |PKC1 |MORE |
Chen Y, et al. (2018) Chemogenomic Profiling of the Fungal Pathogen Candida albicans. Antimicrob Agents Chemother 62(2)
| Large-scale phenotype analysis | C. albicans | |ADP1 |AGM1 |ALO1 |C1_07050C_A |C1_10320W_A |C1_14500C_A |C2_05290C_A |C3_03110W_A |C4_00470C_A |C4_04870C_A |C5_00560W_A |C6_00430C_A |C6_02410W_A |CHS7 |MORE |
El Khoury P, et al. (2018) Proteomic analysis of a Candida albicans pir32 null strain reveals proteins involved in adhesion, filamentation and virulence. PLoS One 13(3):e0194403
| Large-scale protein detection | C. albicans | |ALS3 |CDC42 |CSA2 |DCW1 |DFG5 |PIR32 |RBT5 |SSR1 |SSU81 |UCF1 |XOG1 |
Forche A, et al. (2018) Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans. Genetics 209(3):725-741
| Other genomic analysis | C. albicans | |GAL1 |
Herrero-de-Dios C, et al. (2018) Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs. MBio 9(2)
| Genomic expression study | C. albicans | |HOG1 |
Huang M and Kao KC (2018) Identifying novel genetic determinants for oxidative stress tolerance in Candida glabrata via adaptive laboratory evolution. Yeast 35(11):605-618
| Large-scale phenotype analysis | C. glabrata | |CAGL0C00385g |CAGL0F06831g |CTH2 |
Iracane E, et al. (2018) Identification of an Exceptionally Long Intron in the HAC1 Gene of Candida parapsilosis. mSphere 3(6)
| Genomic expression study | C. albicans | |HAC1 |
| | C. glabrata | |HAC1 |
| | C. parapsilosis | |HAC1 |
Jiang L, et al. (2018) CaGdt1 plays a compensatory role for the calcium pump CaPmr1 in the regulation of calcium signaling and cell wall integrity signaling in Candida albicans. Cell Commun Signal 16(1):33
| Genomic expression study | C. albicans | |C5_05020C_A |CEK1 |CHS2 |CHS3 |CHS8 |DIE2 |GDT1 |MKC1 |PMR1 |PMT1 |PMT4 |STT3 |SWI4 |
Kaneva IN, et al. (2018) Quantitative Proteomic Analysis in Candida albicans Using SILAC-Based Mass Spectrometry. Proteomics 18(5-6):e1700278
| Large-scale protein detection | C. albicans | |ARG4 |CDC14 |
Lee JH, et al. (2018) Antibiofilm and Antivirulence Activities of 6-Gingerol and 6-Shogaol Against Candida albicans Due to Hyphal Inhibition. Front Cell Infect Microbiol 8:299
| Genomic expression study | C. albicans | |CDR1 |CDR2 |ECE1 |HWP1 |RTA3 |
McCall AD, et al. (2018) Candida albicans Sfl1/Sfl2 regulatory network drives the formation of pathogenic microcolonies. PLoS Pathog 14(9):e1007316
| Genomic expression study | C. albicans | |ECE1 |HWP1 |HYR1 |IHD1 |NDT80 |PGA10 |PLB1 |ROB1 |SAP5 |SFL1 |SFL2 |
Mount HO, et al. (2018) Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. PLoS Genet 14(4):e1007319
| Large-scale genetic interaction, Large-scale phenotype analysis | C. albicans | |APM1 |CR_03430W_A |ERG3 |ERG5 |GZF3 |KIC1 |MRR2 |NPR2 |PBS2 |PEP8 |RCY1 |RGD1 |SET6 |SSK2 |MORE |
Nair R, et al. (2018) Identification of genome-wide binding sites of heat shock factor 1, Hsf1, under basal conditions in the human pathogenic yeast, Candida albicans. AMB Express 8(1):116
| Genomic co-immunoprecipitation study | C. albicans | |CTA8 |
O'Meara TR, et al. (2018) High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis. MBio 9(4)
| Large-scale phenotype analysis | C. albicans | |HOG1 |MNN2 |MNN21 |MNN22 |MNN23 |MNN24 |MNN26 |PGA52 |
Schoeters F, et al. (2018) A High-Throughput Candida albicans Two-Hybrid System. mSphere 3(4)
| Large-scale protein interaction | C. albicans | |PCL5 |PCL7 |PHO85 |
Segal ES, et al. (2018) Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans. MBio 9(5)
| Large-scale phenotype analysis | C. albicans | |ASK1 |C1_12660W_A |C1_12810W_A |C2_06230W_A |C6_04120C_A |C7_02460C_A |CDC11 |CDC12 |CDC3 |CLN3 |CR_03740C_A |CR_05100W_A |FAD1 |KRR1 |MORE |
Thakre A, et al. (2018) Limonene inhibits Candida albicans growth by inducing apoptosis. Med Mycol 56(5):565-578
| Large-scale protein detection | C. albicans | |C6_02480W_A |CCT8 |CRN1 |CR_04650W_A |EBP1 |KRE6 |MBF1 |NPL3 |PIL1 |PIN3 |RHR2 |RPL11 |RPL15A |RPL29 |MORE |
Tripathi H and Khan F (2018) Identification of potential inhibitors against nuclear Dam1 complex subunit Ask1 of Candida albicans using virtual screening and MD simulations. Comput Biol Chem 72:33-44
| Computational analysis | C. albicans | |ASK1 |DAM1 |
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