Genome-wide Analysis papers

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Genome-wide AnalysisProteome-wide Analysis
Comparative genomic hybridizationLarge-scale protein detection
Computational analysisLarge-scale protein interaction
Genomic co-immunoprecipitation studyLarge-scale protein localization
Genomic expression studyLarge-scale protein modification
Large-scale genetic interactionOther large-scale proteomic analysis
Large-scale phenotype analysis 
Other genomic analysis 

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ReferenceLiterature TopicSpeciesGenes Addressed
Alkafeef SS, et al. (2020) Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes. PLoS Genet 16(6):e1008881
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Large-scale protein interactionC. albicans |C1_07630W_A |GRX3 |HAP43 |SFU1
Alves R, et al. (2020) Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source. NPJ Biofilms Microbiomes 6:4
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. glabrata |CAGL0F08239g |CAGL0J07980g |CAGL0K10274g |ERG11 |ERG9 |FTR1 |MGE1
Caplan T, et al. (2020) Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2. Cell Chem Biol
CGD Papers Entry  Pubmed Entry  
Large-scale phenotype analysisC. albicans |ALS3 |CHS1 |CHS2 |CHS3 |CHS8 |DDR48 |HRR25 |SOD5 |STP4 |URK1 |YCK2
Dawson CS, et al. (2020) Protein markers for Candida albicans EVs include claudin-like Sur7 family proteins. J Extracell Vesicles 9(1):1750810
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Large-scale protein localizationC. albicans |ARF3 |BGL2 |BRO1 |C1_04200C_A |C2_08160C_A |C4_04800W_A |CAN1 |CAN2 |CDC42 |CDR1 |CDR2 |CHS3 |CRH11 |ECM33 |MORE
Doing G, et al. (2020) Conditional antagonism in co-cultures of Pseudomonas aeruginosa and Candida albicans: An intersection of ethanol and phosphate signaling distilled from dual-seq transcriptomics. PLoS Genet 16(8):e1008783
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Genomic expression studyC. albicans |ADH1 |PHO4
Ev LD, et al. (2020) The role of Candida albicans in root caries biofilms: an RNA-seq analysis. J Appl Oral Sci 28:e20190578
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |ASR1 |C3_01020W_A |C7_03850W_A |GUT1 |HGT19 |ITR1 |STT4 |UTP20
Feng J, et al. (2020) Hof1 plays a checkpoint related role in MMS induced DNA damage response in Candida albicans. Mol Biol Cell :mbcE19060316
CGD Papers Entry  Pubmed Entry  
Large-scale phenotype analysisC. albicans |HOF1 |NOC2 |RAD23 |RAD4 |RAD53
Goncalves B, et al. (2020) Effect of progesterone on Candida albicans biofilm formation under acidic conditions: A transcriptomic analysis. Int J Med Microbiol :151414
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |ADH2 |AGP3 |AHR1 |ALS1 |ALS5 |ATO1 |ATP6 |ATP9 |BRG1 |C1_00160C_A |C1_01130W_A |C1_01630W_A |C1_07160C_A |C1_13130C_A |MORE
Gong J, et al. (2020) The Als3 cell wall adhesin plays a critical role in human Serum amyloid A1 (SAA1)-induced cell death and aggregation in Candida albicans. Antimicrob Agents Chemother
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Genomic expression studyC. albicans |AHR1 |ALS3 |BCR1 |EFG1
Jenull S, et al. (2020) ATAC-Seq Identifies Chromatin Landscapes Linked to the Regulation of Oxidative Stress in the Human Fungal Pathogen Candida albicans J Fungi (Basel) 6:E182
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Other genomic analysisC. albicans |CAP1
Khemiri I, et al. (2020) Transcriptome Analysis Uncovers a Link Between Copper Metabolism, and Both Fungal Fitness and Antifungal Sensitivity in the Opportunistic Yeast Candida albicans. Front Microbiol 11:935
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Genomic expression studyC. albicans |ATX1 |CRP1 |CTR1 |CUP1 |FRE7 |MAC1
Lagree K, et al. (2020) Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. PLoS Genet 16(1):e1008582
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Genomic expression studyC. albicans |CDC19 |CTN1 |ENO1 |FOX2 |GAL1 |GPM1 |HGT1 |HXK2 |ICL1 |MIG1 |MIG2 |MLS1 |PFK1 |PFK2 |MORE
Marton T, et al. (2020) Use of CRISPR-Cas9 To Target Homologous Recombination Limits Transformation-Induced Genomic Changes in Candida albicans mSphere 5:e00620-20
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Large-scale phenotype analysisC. albicans |CDR3 |RPS1
Miramon P, et al. (2020) The paralogous transcription factors Stp1 and Stp2 of Candida albicans have distinct functions in nutrient acquisition and host interaction. Infect Immun
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |PTR3 |SFL2 |SSY1 |SSY5 |STP1 |STP2 |UME6
Rasheed M, et al. (2020) Global Secretome Characterization of the Pathogenic Yeast Candida glabrata. J Proteome Res 19(1):49-63
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Large-scale protein localizationC. glabrata |ACT1 |ADH1 |AHP1 |CAGL0A00979g |CAGL0A01474g |CAGL0A01540g |CAGL0A01870g |CAGL0A03117g |CAGL0A03278g |CAGL0B01100g |CAGL0C02453g |CAGL0C02475g |CAGL0C04389g |CAGL0C04411g |MORE
Sitterle E, et al. (2020) Large-scale genome mining allows identification of neutral polymorphisms and novel resistance mutations in genes involved in Candida albicans resistance to azoles and echinocandins. J Antimicrob Chemother
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Other genomic analysisC. albicans |ERG11 |GSC1 |GSL1 |MRR1 |TAC1 |UPC2
Thakre A, et al. (2020) Oxidative stress induced by piperine leads to apoptosis in Candida albicans. Med Mycol
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |C1_01490W_A |C2_07070W_A |C6_04290W_A |CAT2 |CDC37 |FRS2 |GDH2 |GLO3 |MCA1 |MNT1 |PEX19 |PYC2 |RPN1 |SDH2 |MORE
Thomas G, et al. (2020) Identifying Candida albicans Gene Networks Involved in Pathogenicity. Front Genet 11:375
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Computational analysis, Genomic expression studyC. albicans |AHR1 |CST20 |GRR1 |HGC1 |HIT1 |HOG1 |HST7 |HWP1 |INT1 |PBS2 |PEP8 |RIM101 |RSR1 |SEF1 |MORE
Truong T, et al. (2020) Proteomics Analysis of Candida albicans dnm1 Haploid Mutant Unraveled the Association Between Mitochondrial Fission and Antifungal Susceptibility. Proteomics :e1900240
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Large-scale protein detection, Genomic expression studyC. albicans |DNM1
Verma R, et al. (2020) Genome-wide screening and in silico gene knockout to predict potential candidates for drug designing against Candida albicans. Infect Genet Evol :104196
CGD Papers Entry  Pubmed Entry  
Computational analysisC. albicans |ERG5 |FAS2 |FOL1
Wakade RS, et al. (2020) The Ndr/LATS Kinase Cbk1 Regulates a Specific Subset of Ace2 Functions and Suppresses the Hypha-to-Yeast Transition in Candida albicans. MBio 11(4)
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Genomic expression studyC. albicans |ACE2 |CBK1 |PES1 |SNF5
Wallace EWJ, et al. (2020) Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom. Nucleic Acids Res 48(5):2312-2331
CGD Papers Entry  Pubmed Entry  
Computational analysis
Xu H, et al. (2020) RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans. Cell Commun Signal 18(1):1
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Genomic expression studyC. albicans |CRZ1
Yang D, et al. (2020) Candida albicans Ubiquitin and Heat Shock Factor-Type Transcriptional Factors Are Involved in 2-Dodecenoic Acid-Mediated Inhibition of Hyphal Growth. Microorganisms 8(1)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |SFL1 |SFL2 |UBI4
Barber AE, et al. (2019) Comparative Genomics of Serial Candida glabrata Isolates and the Rapid Acquisition of Echinocandin Resistance during Therapy. Antimicrob Agents Chemother 63(2)
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Other genomic analysisC. glabrata |FKS2 |FPR1 |MDE1
Bravo Ruiz G, et al. (2019) Rapid and extensive karyotype diversification in haploid clinical Candida auris isolates. Curr Genet 65(5):1217-1228
CGD Papers Entry  Pubmed Entry  
Other genomic analysis
Carrete L, et al. (2019) Genome Comparisons of Candida glabrata Serial Clinical Isolates Reveal Patterns of Genetic Variation in Infecting Clonal Populations. Front Microbiol 10:112
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Other genomic analysisC. albicans |CDR1 |CDR2 |ERG11 |ERG3 |ERG9 |FEN1 |GSL2 |QDR2 |SNQ2
C. glabrata |CAGL0B00242g |CAGL0F09273g |CAGL0J01774g |CAGL0J02530g |CAGL0L00227g |CAGL0M08756g |CDR1 |ERG11 |ERG3 |ERG9 |FEN1 |FKS1 |FKS2 |FLR1 |MORE
Castanheira M, et al. (2019) Analysis of Global Antifungal Surveillance Results Reveals Predominance of Erg11 Y132F Alteration among Azole-Resistant Candida parapsilosis and Candida tropicalis and Country-Specific Isolate Dissemination. Int J Antimicrob Agents
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. albicans |CDR1 |ERG11 |MDR1
C. glabrata |CDR1 |ERG11
C. parapsilosis |CDR1 |ERG11 |MDR1
C. dubliniensis |CDR1 |Cd36_84000 |ERG11 |MDR1
Chinnici J, et al. (2019) Candida albicans cell wall integrity transcription factors regulate polymicrobial biofilm formation with Streptococcus gordonii. PeerJ 7:e7870
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |ACE2 |ASH1 |BAS1 |BCR1 |BRG1 |CAS5 |CPH2 |CRZ1 |CSR1 |CTA4 |CUP9 |CWT1 |CZF1 |EFG1 |MORE
Cottier F, et al. (2019) Remasking of Candida albicans beta-Glucan in Response to Environmental pH Is Regulated by Quorum Sensing. MBio 10(5)
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Genomic expression studyC. albicans |CHT2 |EFG1
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